PMID: 18710131Aug 20, 2008Paper

Photoangiolytic laser treatment of early glottic cancer: a new management strategy

The Annals of Otology, Rhinology & Laryngology. Supplement
Steven M ZeitelsRobert E Hillman

Abstract

The 532 nm pulsed KTP (potassium titanyl phosphate) laser and the 585 nm pulsed dye laser (PDL) are photoangiolytic lasers that have been demonstrated to be effective for managing vocal fold dysplasia. The putative mechanism of action is selective photoangiolysis of the sublesional microcirculation. On the basis of this experience, early glottic cancers were treated by selectively targeting the intralesional and sublesional microvasculature. This approach was derived from Folkman's concepts of neoplastic growth resulting from tumor angiogenesis. Staged microlaryngeal treatment was adopted, because it facilitated optimal functional results, and was considered safe, because early glottic cancer rarely metastasizes. Furthermore, intercurrent disease during conventional incremental radiotherapy is typical in treating early glottic cancer. A pilot group of 22 patients with early glottic cancer (13 T1, 9 T2) were treated with a fiber-based angiolytic laser. Eleven of the 22 had unilateral disease and were entirely treated by laser photoangiolysis as a sole modality. Eleven of the 22 had bilateral disease; 5 of the 11 were treated entirely (bilaterally) by laser photoangiolysis, and 6 of the 11 only underwent laser treatment of the le...Continue Reading

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References

Oct 1, 1978·American Journal of Surgery·C W VaughanG J Jako
Aug 1, 1975·The Laryngoscope·M S Strong
Feb 1, 1992·The Annals of Otology, Rhinology, and Laryngology·H E Eckel, W F Thumfart
Sep 1, 1991·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·S M Zeitels, C W Vaughan
Feb 1, 1988·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·J J LehmanJ H Brandenburg
Aug 1, 1988·The Journal of the Acoustical Society of America·E B HolmbergJ S Perkell
Nov 1, 1985·The Annals of Otology, Rhinology, and Laryngology·M HiranoO Tateishi
Nov 18, 1971·The New England Journal of Medicine·J Folkman
Jan 1, 1983·Lasers in Surgery and Medicine·R R AndersonJ A Parrish
Sep 1, 1994·The Annals of Otology, Rhinology, and Laryngology·S M Zeitels, C W Vaughan
Mar 1, 1993·American Journal of Otolaryngology·W Steiner
Dec 1, 1996·American Journal of Surgery·S M Zeitels
Jan 1, 1997·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·M RemacleM Delos
Apr 25, 2000·The Annals of Otology, Rhinology, and Laryngology·R B Desloge, S M Zeitels
Oct 5, 2001·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·M RamacleJ Jamart
Jan 22, 2002·The Laryngoscope·S M ZeitelsR A Franco
Feb 25, 2003·The Annals of Otology, Rhinology, and Laryngology·Steven M ZeitelsSeth H Dailey
Aug 29, 2003·The New England Journal of Medicine·Steven M Zeitels, Gerald B Healy
Oct 1, 1953·The British Journal of Radiology·M LEDERMAN, C A GREATOREX
Oct 11, 2003·The Annals of Otology, Rhinology, and Laryngology·Ramon A FrancoR Rox Anderson
Jan 8, 2004·The Laryngoscope·Steven M ZeitelsJames A Burns
Feb 7, 2004·The Annals of Otology, Rhinology, and Laryngology·Steven M ZeitelsSeth H Dailey
Jun 1, 1952·The British Journal of Radiology·D T GREEN, R F FERRINGTON
Apr 29, 2004·The Annals of Otology, Rhinology, and Laryngology·Steven M ZeitelsR Rox Anderson
May 28, 2004·Otolaryngologic Clinics of North America·Steven M Zeitels
Sep 30, 2004·The Laryngoscope·James A BurnsSteven M Zeitels
Feb 14, 2006·Otolaryngologic Clinics of North America·Steven M Zeitels, James A Burns
Aug 12, 2006·The Annals of Otology, Rhinology, and Laryngology·Steven M ZeitelsWilliam Faquin
Oct 19, 2006·The Annals of Otology, Rhinology, and Laryngology·Steven M ZeitelsR Rox Anderson
Oct 17, 2007·The Annals of Otology, Rhinology & Laryngology. Supplement·Steven M ZeitelsR Rox Anderson
Nov 8, 2007·Current Opinion in Otolaryngology & Head and Neck Surgery·Steven M Zeitels, James A Burns

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Citations

Sep 14, 2010·Lasers in Medical Science·Marc Rubinstein, William B Armstrong
Jan 9, 2013·Journal of Voice : Official Journal of the Voice Foundation·Xuanqian XieMaurice McGregor
Oct 20, 2010·The Surgical Clinics of North America·Henning A Gaissert, James Burns
Jun 3, 2009·Journal of Voice : Official Journal of the Voice Foundation·Yan YanJack J Jiang
May 1, 2010·Lasers in Surgery and Medicine·Aleksandar J KrmpotVladimir S Trajkovic
Aug 4, 2015·Otolaryngologic Clinics of North America·Steven M Zeitels
Oct 18, 2011·Otolaryngologia polska. The Polish otolaryngology·Andrzej WojdasDariusz Jurkiewiczc
Oct 5, 2015·Journal of Voice : Official Journal of the Voice Foundation·Anthony G Del SignorePeak Woo
Sep 9, 2018·The Laryngoscope·Lauren F TracyJames A Burns
Oct 23, 2018·Technology in Cancer Research & Treatment·Vadim V ElaginVladislav A Kamensky
Dec 6, 2017·Journal of Speech, Language, and Hearing Research : JSLHR·Victoria S McKennaCara E Stepp
May 28, 2010·Neurologia Medico-chirurgica·Jae Eun Kwon, Ealmaan Kim
Apr 13, 2013·The Annals of Otology, Rhinology, and Laryngology·Aaron D FriedmanSteven M Zeitels
Jan 9, 2016·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Yo KishimotoShigeru Hirano
Sep 13, 2017·The Laryngoscope·Jamal AhmedDavid E Rosow
Dec 12, 2018·The Annals of Otology, Rhinology, and Laryngology·S A Reza NouraeiDavid E Vokes
Dec 13, 2019·Lasers in Surgery and Medicine·Yonatan LahavHagit Shoffel-Havakuk
Aug 28, 2020·Laryngo- rhino- otologie·Markus Hess, Susanne Fleischer
Nov 28, 2009·The Journal of Laryngology and Otology·J A BurnsS M Zeitels
May 26, 2012·The Journal of Laryngology and Otology·A D FriedmanS M Zeitels
Aug 30, 2014·The Annals of Otology, Rhinology, and Laryngology·VyVy N YoungClark A Rosen
Jun 28, 2014·The Annals of Otology, Rhinology, and Laryngology·Steven M Zeitels, James A Burns
Feb 7, 2020·Laryngoscope Investigative Otolaryngology·Renee L EigstiHenry T Hoffman
Jan 29, 2016·Acta Oto-laryngologica·Hagit Shoffel-HavakukDoron Halperin
Sep 11, 2019·Photobiomodulation, Photomedicine, and Laser Surgery·Zhewei LouJack J Jiang
Jul 7, 2020·The Annals of Otology, Rhinology, and Laryngology·Noah P ParkerDavid G Lott
May 24, 2013·The Annals of Otology, Rhinology, and Laryngology·Anca M BarbuSteven M Zeitels
Mar 8, 2019·The Annals of Otology, Rhinology, and Laryngology·Semirra BayanSteven M Zeitels
Oct 23, 2009·The Annals of Otology, Rhinology & Laryngology. Supplement·Steven M ZeitelsRobert E Hillman
Sep 24, 2013·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Carolyn A Coughlan, Sunil P Verma
Apr 21, 2018·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Markus M HessMarcel Ernstberger
Jun 6, 2021·The Annals of Otology, Rhinology, and Laryngology·Kenneth Yan, Aaron D Friedman
Aug 24, 2021·The Annals of Otology, Rhinology, and Laryngology·Jiajia WangPeijie He
Nov 30, 2021·Journal of Speech, Language, and Hearing Research : JSLHR·Defne AburCara E Stepp

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