Photodynamic Antimicrobial Chemotherapy for Root Canal System Asepsis: A Narrative Literature Review

International Journal of Dentistry
P DiogoJ M Santos

Abstract

Aim. The aim of this comprehensive literature review was to address the question: Does photodynamic therapy (PDT) improve root canal disinfection through significant bacterial reduction in the root canal system? Methodology. A comprehensive narrative literature review was performed to compare PDT effect with sodium hypochlorite as the comparative classical irrigant. Two reviewers independently conducted literature searches using a combination of medical subject heading terms and key words to identify relevant studies comparing information found in 7 electronic databases from January 2000 to May 2015. A manual search was performed on bibliography of articles collected on electronic databases. Authors were contacted to ask for references of more research not detected on the prior electronic and manual searches. Results. The literature search provided 62 titles and abstracts, from which 29 studies were related directly to the search theme. Considering all publications, 14 (48%) showed PDT to be more efficient in antimicrobial outcome than NaOCl (0.5-6% concentration) used alone and 2 (7%) revealed similar effects between them. Toluidine blue and methylene blue are the most used photosensitizers and most commonly laser has 660 nm o...Continue Reading

References

Jan 1, 1992·Photochemistry and Photobiology·B W Henderson, T J Dougherty
Jan 1, 1987·Annual Review of Microbiology·J W CostertonT J Marrie
Oct 10, 1997·FEMS Immunology and Medical Microbiology·M WainwrightF J Bolton
Mar 6, 1998·Journal of Endodontics·E BeruttiA Angeretti
Mar 6, 1998·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·G H Bowden, I R Hamilton
Jun 24, 1998·Journal of the National Cancer Institute·T J DoughertyQ Peng
Aug 13, 1998·The Journal of Antimicrobial Chemotherapy·M Wainwright
Jul 7, 2001·BMJ : British Medical Journal·P JüniM Egger
Aug 9, 2001·Journal of Endodontics·L B PetersA J van Winkelhoff
Nov 29, 2001·Photochemistry and Photobiology·R AckroydM Reed
May 3, 2002·International Endodontic Journal·M EvansD Figdor
Aug 24, 2002·International Endodontic Journal·I PortenierM Haapasalo
Jun 7, 2003·International Journal of Antimicrobial Agents·Mark Wainwright
May 4, 2004·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Michael Wilson
May 4, 2004·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Michael R Hamblin, Tayyaba Hasan
May 25, 2004·Antimicrobial Agents and Chemotherapy·Joseph M BlissConstantine G Haidaris
Apr 6, 2005·Biochemistry. Biokhimii︠a︡·K Lewis
Jan 24, 2006·Journal of Endodontics·Charles H StuartChristopher B Owatz
Apr 25, 2006·Journal of Endodontics·Matthias Zehnder
Jun 17, 2006·International Endodontic Journal·L BergmansP Lambrechts
Jul 20, 2006·Journal of Medical Microbiology·Mohammed A Al-Fattani, L Julia Douglas
Jul 26, 2006·British Dental Journal·S J BonsorG J Pearson
Sep 20, 2006·Journal of Endodontics·Nikolaos S SoukosPhilip P Stashenko
Sep 26, 2006·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Aguinaldo Silva GarcezMartha Simões Ribeiro
May 19, 2007·Journal of Endodontics·Luis E Chavez de Paz, Luis Chávez de Paz
Jul 20, 2007·Journal of Oral Science·Wen L ChaiMariam Abdullah
Jul 27, 2007·Journal of Dental Research·K Konopka, T Goslinski
Dec 18, 2007·International Endodontic Journal·L BergmansP Lambrechts
Dec 29, 2007·Medicinal Research Reviews·Yong-Gang QiangZheng Huang
Jan 25, 2008·Journal of Endodontics·Aguinaldo Silva GarcezMartha Simões Ribeiro
Apr 26, 2008·Photochemistry and Photobiology·Saji George, Anil Kishen
Oct 7, 2008·Applied and Environmental Microbiology·Malin KvistPer Klemm
Oct 22, 2008·Journal of Endodontics·José F Siqueira, Isabela N Rôças
May 12, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Alper KuştarciSerpil Koşum
May 29, 2009·Australian Dental Journal·Z LimA Kishen
Jun 6, 2009·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Saji GeorgeAnil Kishen

❮ Previous
Next ❯

Citations

Nov 7, 2016·Photodiagnosis and Photodynamic Therapy·Charis BeltesChrissanthy Papadopoulou
Sep 27, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Mariana Q MesquitaM Amparo F Faustino
Jul 13, 2018·Dentistry Journal·Islam A Abdelaziz Ali, Prasanna Neelakantan
Oct 3, 2019·Journal of Functional Biomaterials·Patrícia DiogoJoão Miguel Santos
Jan 26, 2021·International Journal of Microbiology·Jean-Paul RoccaElisabetta Merigo

❮ Previous
Next ❯

Software Mentioned

FotoSan
Denfotex
Helbo
STROBE

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.