Photodynamic Therapy for Basal Cell Carcinoma: The Clinical Context for Future Research Priorities.

Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry
N J Collier, L E Rhodes

Abstract

Photodynamic therapy (PDT) is an established treatment option for low-risk basal cell carcinoma (BCC). BCC is the most common human cancer and also a convenient cancer in which to study PDT treatment. This review clarifies challenges to researchers evident from the clinical use of PDT in BCC treatment. It outlines the context of PDT and how PDT treatments for BCC have been developed hitherto. The sections examine the development of systemic and subsequently topical photosensitizers, light delivery regimens, and the use of PDT in different patient populations and subtypes of BCC. The outcomes of topical PDT are discussed in comparison with alternative treatments, and topical PDT applications in combination and adjuvant therapy are considered. The intention is to summarize the clinical relevance and expose areas of research need in the BCC context, ultimately to facilitate improvements in PDT treatment.

References

Jan 1, 1992·Photochemistry and Photobiology·B W Henderson, T J Dougherty
Jun 1, 1990·Journal of Photochemistry and Photobiology. B, Biology·J C KennedyD C Pross
Jun 24, 1998·Journal of the National Cancer Institute·T J DoughertyQ Peng
Dec 3, 1999·The British Journal of Dermatology·N R TelferP W Bowers
Mar 30, 2000·Journal of Photochemistry and Photobiology. B, Biology·P UehlingerN Lange
Aug 14, 2003·Photodermatology, Photoimmunology & Photomedicine·C ClarkS H Ibbotson
Jan 25, 2005·Clinical and Experimental Dermatology·J T LearA A Fryer
Apr 21, 2005·The British Journal of Dermatology·C VinciulloD Murrell
Feb 1, 2006·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·A Neil Crowson
Mar 18, 2006·Photochemistry and Photobiology·Nicolas FotinosNorbert Lange
May 17, 2006·International Journal of Dermatology·Roger I Ceilley, James Q Del Rosso
Feb 21, 2007·Archives of Dermatology·David VidalAgustín Alomar
Jul 3, 2008·The British Journal of Dermatology·N R TelferUNKNOWN British Association of Dermatologists
Jul 16, 2008·Journal of the European Academy of Dermatology and Venereology : JEADV·R M SzeimiesUNKNOWN Excilight Study Group
Oct 24, 2008·The British Journal of Dermatology·C A MortonUNKNOWN British Association of Dermatologists Therapy Guidelines and Audit Subcommittee and the British Photodermatology Group
Jun 25, 2009·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Edith KabinguSandra O Gollnick
Oct 23, 2010·Expert Opinion on Drug Delivery·Bhupender S Chhikara, Keykavous Parang
Dec 15, 2010·Journal of Skin Cancer·Elizabeth A JonesD Gareth Evans
Mar 16, 2011·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Robert M SayreRonald W Gottschalk
Jul 30, 2011·Journal of the American Academy of Dermatology·Andrea L HawsThuy L Phung
Aug 11, 2011·Biochemical Pharmacology·Brahma N SinghRakesh K Srivastava
Feb 2, 2012·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Beata OsieckaPiotr Ziółkowski
Apr 11, 2012·Biochemical and Biophysical Research Communications·Na Young MinKwang-Ho Lee
Sep 14, 2012·Photodermatology, Photoimmunology & Photomedicine·Sally Helen Ibbotson, James Ferguson
Sep 14, 2012·Photodermatology, Photoimmunology & Photomedicine·Sally H IbbotsonRoss Hearn
Oct 6, 2012·Advanced Drug Delivery Reviews·Theresa M Allen, Pieter R Cullis
Jan 9, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·S R WiegellH C Wulf
Apr 16, 2013·Journal of the European Academy of Dermatology and Venereology : JEADV·N Basset-SeguinS Piaserico
Apr 24, 2013·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Sophie C FlohilTamar Nijsten

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Methods Mentioned

BETA
scraping
biopsies

Clinical Trials Mentioned

NCT03053635
NCT03573401
NCT03467789

Related Concepts

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Carcinoma, Basal Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

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