Photodynamic therapy for predominantly hemorrhagic lesions in neovascular age-related macular degeneration

American Journal of Ophthalmology
Saad AhmadSharon Fekrat

Abstract

To evaluate the response of eyes treated with photodynamic therapy (PDT) for predominantly hemorrhagic lesions in neovascular age-related macular degeneration (NVAMD). Consecutive, interventional case series. A retrospective review was conducted of eyes with NVAMD that were treated with PDT for predominantly hemorrhagic subfoveal lesions. Baseline data recorded were patient age, use of aspirin or warfarin, history of previous PDT treatment, visual acuity (VA), extent of subretinal hemorrhage (SRH), and central foveal thickness (CFT) and total macular volume (TMV) measured by optical coherence tomography (OCT). Follow-up VA, SRH status, and complications were recorded. Twenty-one eyes of 21 patients were identified with a mean posttreatment follow-up of 9.4 months. Mean pretreatment VA was 20/210, and mean SRH size was 16 disk areas. The SRH resolved in 18 eyes (86%) after a mean of six months, with a mean VA of 20/210. Mean VA for all eyes at most recent follow-up was 20/250. Thirteen (62%) of 21 eyes exhibited stable or improved VA at the most recent follow-up. VA one year after PDT inversely correlated with patient age (P = .045) and initial SRH size (P = .04) and positively correlated with pretreatment VA (P = .01). Previous...Continue Reading

References

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Citations

May 29, 2012·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Chui Ming Gemmy CheungTien Yin Wong
Apr 24, 2010·Lasers in Medical Science·Jong-Hwan ParkJung-Hoon Yoon
Jul 28, 2015·Survey of Ophthalmology·Dinu Stanescu-SegallTimothy L Jackson
Mar 21, 2016·Journal français d'ophtalmologie·R BouraouiL El Matri
Nov 3, 2011·Seminars in Ophthalmology·Ryan W Shultz, Sophie J Bakri
Apr 1, 2020·Medwave·Jaime Leonel Quiroz-MendozaRenata García-Franco

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