PMID: 6397270Jan 1, 1984Paper

Photodynamic therapy (PDT) of malignant tumors

Critical Reviews in Oncology/hematology
Thomas J Dougherty

Abstract

Photodynamic therapy (PDT) is finding increasing application to a number of malignant tumors. It is based on the specific photosensitization of malignant tissue by a particular porphyrin derived from hematoporphyrin, known as Photofrin II. The exact structure at present is unknown. However this material, following systemic injection, is retained longer in malignant tissue than in many normal tissues and can be activated by visible light, usually red, to initiate a lethal phototoxic effect on the tumor. It is a particularly useful treatment when specificity is necessary in treatment, for example in treatment of widespread chest wall metastasis, bladder cancer and early lesions of the bronchus, trachea and esophagus, including CIS.

References

Jul 1, 1979·Chest·D R DoironT J Dougherty
Jan 1, 1982·Lasers in Surgery and Medicine·A G WileM W Berns
Jan 1, 1983·Medical Physics·L O SvaasandT J Dougherty
Jul 1, 1982·Photochemistry and Photobiology·D A Bellnier, T J Dougherty
Jan 1, 1980·Biochimica Et Biophysica Acta·T M DubbelmanJ Van Steveninck
Sep 1, 1980·Photochemistry and Photobiology·C J Gomer, D M Smith
Jul 1, 1948·Proceedings of the Society for Experimental Biology and Medicine·F H J FIGGEL O J MANGANIELLO

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Citations

Jan 1, 1986·The International Journal of Biochemistry·A M BatlleA M Stella
Jan 1, 1994·Pharmacology & Therapeutics·Z Diwu, J W Lown
Mar 1, 1990·Journal of Biochemical and Biophysical Methods·A AndreoniP Russo
Jan 1, 1983·International Journal of Immunopharmacology·P FrancoG Canti
Jan 1, 1995·International Journal of Immunopharmacology·D W HuntJ G Levy
May 1, 1990·Journal of Photochemistry and Photobiology. B, Biology·S MenezesL R Caldas
May 15, 1992·Journal of Photochemistry and Photobiology. B, Biology·N YamamotoT Kimoto
Nov 29, 2013·Photodiagnosis and Photodynamic Therapy·Ron R Allison, Keyvan Moghissi
Feb 12, 1998·Cancer Letters·A CasasA M del C Batlle
Apr 17, 1999·Journal of Photochemistry and Photobiology. B, Biology·R DecreauM Julliard
Dec 1, 2004·Photodiagnosis and Photodynamic Therapy·R R AllisonC H Sibata
Feb 8, 2011·Journal of the American Chemical Society·Yu ChengClemens Burda
Oct 15, 2013·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Kate RossNeil Fenske
Sep 1, 1992·Journal of Veterinary Pharmacology and Therapeutics·D L FrazierB F Overholt
Sep 1, 1992·International Journal of Dermatology·T S Alster, S R Kohn
Jun 1, 1984·Photochemistry and Photobiology·D Kessel
Nov 1, 1987·Photochemistry and Photobiology·W M StarM J van Gemert
Nov 1, 1987·Photochemistry and Photobiology·J W Winkelman, G H Collins
Nov 1, 1987·Photochemistry and Photobiology·C J GomerA L Murphree
Nov 1, 1987·Photochemistry and Photobiology·J F Evensen, J Moan
Jun 1, 1987·Photochemistry and Photobiology·D KesselK D Nantwi
Jun 1, 1988·Photochemistry and Photobiology·R K Pandey, T J Dougherty
Sep 1, 1988·Photochemistry and Photobiology·E MelloniR Marchesini
Sep 1, 1990·Photochemistry and Photobiology·W StarH Marijnissen
Aug 1, 1990·Photochemistry and Photobiology·G Jori
Sep 1, 1991·Photochemistry and Photobiology·D Kessel
Aug 1, 1992·Photochemistry and Photobiology·N YamamotoS Yamamoto
Sep 21, 2007·Photochemistry and Photobiology·Sarika VermaTayyaba Hasan
Dec 17, 2011·Photochemistry and Photobiology·Daiva DabkevicieneVida Kirveliene
Aug 25, 2005·Oncology·Satoshi YamaguchiRyuichiro Nishimura

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