PMID: 8949443Sep 1, 1996Paper

Photodynamic therapy with 5-aminolevulinic acid in the treatment of actinic cheilitis

The British Journal of Dermatology
I M Stender, H C Wulf

Abstract

Three patients with cheilitis were successfully treated by photodynamic therapy using the topical application of 5-aminolevulinic acid (ALA), followed by irradiation with incoherent visible light. The three patients had had, for several years, disabling lesions on the lower lip, and histopathological examination showed dysplastic lesions without signs of carcinoma. Conventional treatments were ineffective. During photodynamic therapy, all patients reported a burning sensation when irradiated at the ALA treated area, diminishing immediately after removal of the light source, and vanishing within 4 days after treatment. Superficial peeling began 4 days after treatment, and lasted some months. Follow-up, after 6 and 12 months, did not reveal any sign of recurrence.

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Citations

Aug 2, 2001·Clinics in Dermatology·N C ZeitouniA R Oseroff
Nov 19, 2002·Clinics in Dermatology·Katrin A Salva
Nov 14, 2001·American Journal of Clinical Dermatology·S KarrerM Landthaler
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Mar 28, 2008·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Raymond G DufresneNathaniel J Jellinek
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May 7, 2009·The Journal of Dermatological Treatment·Iria CastiñeirasEduardo Fonseca
Jan 5, 2002·Expert Opinion on Investigational Drugs·S A Doggrell
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Oct 11, 2008·Dermatologic Therapy·R RossiT Lotti
Jun 21, 2012·Anais Brasileiros De Dermatologia·Camila Ferrari RibeiroLuciana Lisboa Faucz
Jul 1, 1997·Dermatologic Clinics·R Bissonnette, H Lui
Nov 20, 2016·Photodermatology, Photoimmunology & Photomedicine·Yuri N ChavesCyro Festa Neto
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Apr 23, 2002·The British Journal of Dermatology·Colin A MortonL E Rhodes
May 1, 2015·Journal of Cutaneous Medicine and Surgery·Yves PoulinUNKNOWN Canadian non-Melanoma Skin Cancer Guidelines Committee
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Jan 30, 2015·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Mohammad-Ali Yazdani AbyanehKeyvan Nouri

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