Photodynamic therapy with verteporfin for subfoveal choroidal neovascularisation of pathologic myopia in Chinese eyes: a prospective series of 1 and 2 year follow up

The British Journal of Ophthalmology
D S C LamK K L Chong

Abstract

To evaluate the visual and fluorescein angiographic outcomes of photodynamic therapy (PDT) with verteporfin in patients with subfoveal choroidal neovascularisation (CNV) caused by pathologic myopia in the Chinese. Prospective, non-comparative, two centre interventional study. Patients with CNV secondary to pathologic myopia of Chinese ethnicity were recruited and treated with a standard regimen of PDT with verteporfin. Results of this study in Chinese eyes with pigmented retinal pigment epithelium were compared with those from the Verteporfin in Photodynamic Therapy (VIP) Study of predominantly white eyes. Thirty one and 22 eyes that completed the 12 month and 24 month follow up studies respectively were analysed. The mean and median best corrected visual acuities (BCVA) could be maintained at the baseline level at the 12 month and 24 month visits. Fourteen (63.6%) eyes had stable or improved BCVA at 24 months and six (27.3%) of them had a moderate gain in vision (improved by three or more lines). Visual results were comparable with that of the VIP study, but the average accumulative PDT treatments required in one and two years were 1.7 and 2.3 respectively, which were significantly less than 3.4 and 5.1 treatments in VIP study...Continue Reading

References

May 1, 1979·Ophthalmology·B J Curtin
Jan 1, 1992·Retina·H E Grossniklaus, W R Green
Dec 1, 1984·Ophthalmology·M P AvilaC L Schepens
Aug 1, 1983·Ophthalmology·G R HamptonA C Bird
Mar 1, 1983·Archives of Ophthalmology·R D SperdutoM Rowland
Jan 1, 1982·International Ophthalmology Clinics·P K KuoB F Wu
May 3, 2000·Seminars in Ophthalmology·J Roider
May 15, 2001·International Journal of Cancer. Journal International Du Cancer·C M VajdicB K Armstrong
Aug 25, 2001·The British Journal of Ophthalmology·J M Ruiz-Moreno, C de la Vega
Jan 25, 2003·The British Journal of Ophthalmology·J A Montero, J M Ruiz-Moreno
Feb 20, 2003·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Larry BaumChi Pui Pang
May 8, 2003·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Joachim WachtlinMichael H Foerster
Jul 18, 2003·Ophthalmology·Takeshi YoshidaManabu Mochizuki

❮ Previous
Next ❯

Citations

Sep 1, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ute E K SchnurrbuschSebastian Wolf
Mar 9, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kyoko Ohno-MatsuiManabu Mochizuki
Apr 22, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Ariko KojimaManabu Mochizuki
Jan 17, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Kengo HayashiManabu Mochizuki
Nov 17, 2009·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Gianluca BesozziFrancesco Boscia
Apr 13, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Leila El MatriMejda Bouladi
Dec 14, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·D Mitry, H Zambarakji
Apr 11, 2006·Japanese Journal of Ophthalmology·Wai-Man ChanDennis S C Lam
Jul 21, 2011·Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics·Chih-Hsin ChenHsi-Kung Kuo
Oct 20, 2005·The British Journal of Ophthalmology·W-M ChanD S C Lam
Aug 27, 2015·International Journal of Molecular Sciences·Francesco ParmeggianiPaolo Perri
Sep 10, 2011·Clinical & Experimental Ophthalmology·Danny S NgClement W Chan
Oct 22, 2013·Progress in Retinal and Eye Research·Patrycja Nowak-SliwinskaAdrian H C Koh
Jul 6, 2014·The British Journal of Ophthalmology·Tien Y WongAdnan Tufail
Aug 1, 2012·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·Rufino Silva
Mar 1, 2014·Asia-Pacific Journal of Ophthalmology·Mary HoDennis S C Lam
Sep 15, 2011·Molecular Diagnosis & Therapy·Francesco ParmeggianiCarlo Incorvaia
Oct 21, 2020·BMC Ophthalmology·Amin E Nawar, Heba M Shafik

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.