Photoexcitation of Adenosine 5'-Triphosphate Anions in Vacuo: Probing the Influence of Charge State on the UV Photophysics of Adenine

The Journal of Physical Chemistry. B
Rosaria CercolaCaroline E H Dessent

Abstract

We report the first UV laser photodissociation spectra (4.0-5.8 eV) of gas-phase deprotonated adenosine 5'-triphosphate, diphosphate and monophosphate anions. The photodepletion spectra of these anions display strong absorption bands across the region of 4.6-5.2 eV, consistent with excitation of a primarily adenine-centered π-π* transition. The spectra appear insensitive to the charge of the species (i.e., the spectrum of [ATP-2H]2- closely resembles that of [ATP-H]-), while the spectral profile is affected to a greater extent by the variation of the molecular structure, i.e. the [AMP-H]- and [ADP-H]- photodepletion spectra display similar profiles while the [ATP-H]- spectrum is distinctive. The photodepletion cross-section also decreases for the ATP anions compared to both the AMP and ADP anions, reflecting a high intrinsic photostability of ATP versus both AMP and ADP. A range of photofragments are produced across the 4.0-5.8 eV spectral range for all of the ATP analogues studied. These fragments are primarily associated with fragmentation on the ground-state electronic surface, indicative of a statistical decay process where ultrafast decay is followed by ergodic dissociation. However, while the photofragments observed follo...Continue Reading

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Citations

Nov 7, 2018·Physical Chemistry Chemical Physics : PCCP·Rianne E van OutersterpAnouk M Rijs
Apr 30, 2019·Faraday Discussions·Steven DalyValérie Gabelica
Aug 17, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Edward MatthewsCaroline E H Dessent
Jul 16, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Kelechi O UleanyaCaroline E H Dessent
Nov 25, 2020·Physical Chemistry Chemical Physics : PCCP·Jennifer A NobleChristophe Jouvet
Mar 16, 2021·The Journal of Physical Chemistry Letters·Natalie G K WongCaroline E H Dessent
Apr 23, 2021·The Journal of Physical Chemistry. a·Maria Elena CastellaniJan R R Verlet
Aug 4, 2021·The Journal of Physical Chemistry. a·Natalie G K WongCaroline E H Dessent
Sep 5, 2020·The Journal of Physical Chemistry Letters·Maria Elena CastellaniJan R R Verlet

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