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Photoexcited Toluidine Blue Inhibits Tau Aggregation in Alzheimer's Disease

ACS Omega

Nov 12, 2019

Tushar DubeySubashchandrabose Chinnathambi

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Abstract

The aggregates of microtubule-associated protein Tau are considered as a major hallmark of Alzheimer's disease. Tau aggregates accumulate intracellularly leading to neuronal toxicity. Numerous approaches have been targeted against Tau protein aggregation, which include application of sy...read more

Mentioned in this Paper

Alzheimer's Disease
Cell Death
Circular Dichroism
Cytoskeleton
Drosophila
Dyes
Electrophoresis
Methylene blue
Electron Microscopy
Neurons
2
1
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Photoexcited Toluidine Blue Inhibits Tau Aggregation in Alzheimer's Disease

ACS Omega

Nov 12, 2019

Tushar DubeySubashchandrabose Chinnathambi

PMID: 31737841

DOI: 10.1021/acsomega.9b02792

Abstract

The aggregates of microtubule-associated protein Tau are considered as a major hallmark of Alzheimer's disease. Tau aggregates accumulate intracellularly leading to neuronal toxicity. Numerous approaches have been targeted against Tau protein aggregation, which include application of sy...read more

Mentioned in this Paper

Alzheimer's Disease
Cell Death
Circular Dichroism
Cytoskeleton
Drosophila
2
1

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