Photoperiodic modulation of GnRH mRNA in the male Syrian hamster

Brain Research. Molecular Brain Research
D I BrownH F Urbanski

Abstract

Male Syrian hamsters (Mesocricetus auratus) are seasonal breeders. They show marked testicular regression when exposed to short autumnal photoperiods, and then remain sexually quiescent for several months. By mid-winter, however, they show a loss in responsiveness to the inhibitory influence of short photoperiods and their testes begin to recrudesce. To shed light on the neuroendocrine mechanism responsible for mediating these reproductive changes, we examined the influence of photoperiod on the expression of GnRH mRNA in the hamster forebrain. Adult males were either exposed to short photoperiods (6L:18D) for 16 weeks or were maintained under long photoperiods (14L:10D); additional animals were exposed to short or long photoperiods for 22 weeks. As expected, exposure to short photoperiods for 12 weeks resulted in a marked decrease (P<0.01) in testicular mass and serum testosterone levels, but after 22 weeks these reproductive parameters were once again significantly elevated (P<0.01). In contrast, quantitative in situ hybridization histochemistry revealed no difference (P>0.05) between the GnRH mRNA levels of the short-photoperiod hamsters and their aged-matched long-photoperiod controls, although an age-related decrease (P<0....Continue Reading

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Citations

Mar 24, 2007·Reviews in Endocrine & Metabolic Disorders·Florent G RevelValérie Simonneaux
May 12, 2006·Chronobiology International·Florent G RevelValérie Simonneaux
Jul 5, 2005·Animal Reproduction Science·Iain J Clarke, Sueli Pompolo
Oct 2, 2007·Trends in Neurosciences·Alexander S KauffmanRobert A Steiner
Jun 18, 2019·American Journal of Reproductive Immunology : AJRI·Christian Urias-CastroTerry M Nett
Jun 19, 2004·Archives of Andrology·I KusM Sarsilmaz

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