Photorefractive keratectomy with mitomycin C after deep anterior lamellar keratoplasty for keratoconus

Cornea
Antonio Leccisotti

Abstract

To evaluate the safety and efficacy of photorefractive keratectomy (PRK) with intraoperative mitomycin C (MMC) after deep anterior lamellar keratoplasty (DALK) for keratoconus. This was a prospective, noncomparative single-surgeon study. Eyes with compound myopic astigmatism after DALK with a spherical equivalent (SE) between -3 and -10 D were treated by PRK. After ablation, MMC 0.2 mg/mL was placed on the stromal bed for 45 seconds. A 6% undercorrection was planned. The study was completed on 10 eyes of 10 patients. The preoperative mean SE was -4.98 +/- 1.75 (SD) D. At 10 months after surgery, the mean SE was 0.28 +/- 0.61 D, and the mean defocus equivalent was 1.08 +/- 0.58 D. Postoperatively, 9 eyes were within 2 D, 6 were within 1 D, and 1 eye was within 0.5 D of defocus equivalent. The preoperative mean best spectacle-corrected visual acuity (BSCVA) was 0.68 +/- 0.15 D, and at 10 months it was 0.78 +/- 0.13 D. The 95% confidence interval for the mean difference of pre- and postoperative BSCVA was 0.02-0.17 (P < 0.05). No lines of BSCVA were lost. The mean postoperative uncorrected visual acuity was 0.55 +/- 0.1. The safety index was 1.15, and the efficacy index was 0.81. Corneal haze was grade 0 in 8 eyes and grade 0.5 in...Continue Reading

References

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Citations

Jul 16, 2010·Cornea·Adriana dos Santos ForsetoWalton Nosé
Dec 14, 2011·Cornea·Marcony R SanthiagoSteven E Wilson
May 15, 2010·Current Opinion in Ophthalmology·Jocelyn Kuryan, Prabjot Channa
Dec 12, 2012·Survey of Ophthalmology·Jorge L Alio, Jaime Javaloy
May 26, 2012·Journal of Cataract and Refractive Surgery·Banu Torun AcarFerda Ciftci
Sep 21, 2011·Journal of Cataract and Refractive Surgery·Chris HodgeChris Rogers
Mar 17, 2010·Journal of Refractive Surgery·Irina S BarequetSamuel Levinger
May 10, 2013·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·David P S O'Brart
Jun 24, 2010·American Journal of Ophthalmology·Laura de Benito-Llopis, Miguel A Teus
Jul 15, 2015·American Journal of Ophthalmology·Sepehr Feizi, Mohammad Ali Javadi
Jul 7, 2018·Cornea·Mohammad Ali JavadiPejman Khajuee-Kermani
Dec 24, 2011·Journal of Strength and Conditioning Research·Andréia Silveira de SouzaLuiz Fernando Martins Kruel
May 16, 2020·Current Opinion in Ophthalmology·Angeli Christy YuMassimo Busin
Jun 19, 2009·Current Opinion in Ophthalmology

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