Photorefractive keratectomy with mitomycin C after penetrating and lamellar keratoplasty

Cornea
Adriana dos Santos ForsetoWalton Nosé

Abstract

To assess the safety and efficacy of photorefractive keratectomy with mitomycin C (PRK-MMC) to correct refractive errors after corneal transplantation. This was a prospective and noncomparative study of 36 eyes that underwent PRK-MMC after penetrating (n = 34) or lamellar (n = 2) keratoplasty. After mechanical epithelial removal and photoablation, a sponge with mitomycin C 0.02% was applied to the stromal bed for 1 minute. The uncorrected and best-corrected visual acuities, refraction, and complications were assessed. The average follow-up was 16.27 ± 8.38 months (range, 6-30.5 months). The spherical equivalent decreased from -3.95 ± 4.11 to -1.07 ± 1.45 diopters (D) postoperatively (P < 0.001). The mean preoperative astigmatism was 4.42 ± 1.69 D (range, 1.00-7.25 D); however, surgical correction was limited to 6.00 D. Vector analysis of astigmatic correction showed an index of success of 55%. At the last follow-up, 41.7% (n = 15) and 61.1% (n = 22) of the eyes were within ±0.50 and ±1.00 D of emmetropia, respectively. Nineteen eyes (52.8%) achieved an uncorrected visual acuity of 20/40 or better. The best-corrected visual acuity remained within 1 line of the preoperative values in 26 cases (72.2%), improved in 8 (22.2%), and d...Continue Reading

References

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Citations

Dec 14, 2011·Cornea·Marcony R SanthiagoSteven E Wilson
Dec 12, 2012·Survey of Ophthalmology·Jorge L Alio, Jaime Javaloy
Sep 21, 2011·Journal of Cataract and Refractive Surgery·Chris HodgeChris Rogers
May 10, 2013·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·David P S O'Brart
Dec 24, 2011·Journal of Strength and Conditioning Research·Andréia Silveira de SouzaLuiz Fernando Martins Kruel
May 16, 2020·Current Opinion in Ophthalmology·Angeli Christy YuMassimo Busin

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