Photoresponsive self-healing supramolecular hydrogels for light-induced release of DNA and doxorubicin

Chemical Communications : Chem Comm
Zbigniew L PianowskiKnut Schneider

Abstract

An azobenzene-containing cyclic dipeptide PAP-DKP-Lys is a photoresponsive low-MW hydrogelator. The gelation process can be triggered with temperature, pH, light, and ionic strength. The resulting self-healing gels can encapsulate dsDNA or an anticancer drug doxorubicin, and release them in a light-dependent manner.

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