Photoselective vaporization of the prostate for the treatment of benign prostatic hyperplasia: 12-month results from the first United States multicenter prospective trial

The Journal of Urology
Alexis E TeR S Malek

Abstract

We report the 1-year efficacy and safety of photoselective vaporization of the prostate (PVP) for symptomatic and obstructive benign prostatic hyperplasia (BPH). A prospective clinical trial was performed in 139 men clinically diagnosed with symptomatic bladder outlet obstruction secondary to BPH who were enrolled and treated with a high power, 80 W, quasicontinuous wave potassium-titanyl-phosphate laser at 6 American medical centers across the country. Efficacy parameters were mean and percent changes from baseline in the American Urological Association Symptom Index (AUA-SI) score, quality of life score (QOL), peak urinary flow rate (Qmax), post-void residual urine volume (PVR) and transrectal ultrasound prostate volume measurement. Patients were evaluated 1, 3, 6 and 12 months following treatment. At each followup evaluation side effects were elicited. Significant improvements in AUA-SI score, QOL score, Qmax and PVR were noted as early as 1 month after PVP treatment. At 12 months the mean AUA-SI score decreased from 23.9 to 4.3 (p <0.0001) and the QOL score decreased from 4.3 to 1.1 (p <0.0001), while mean Qmax increased from 7.8 to 22.6 ml per second (p <0.0001). PVR decreased from 114.3 to 24.8 ml (p <0.0001), while the t...Continue Reading

References

Jun 1, 1992·British Journal of Urology·A J CostelloJ Burt
May 8, 2000·The Journal of Urology·R S MalekD M Barrett
Dec 18, 2001·The Journal of Urology·Feridun SengörKubilay Erdoğan
Jul 9, 2002·Urology·Andrew H H Tan, Peter J Gilling

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Citations

Jun 22, 2006·Der Urologe. Ausg. A·O ReichC Stief
Mar 21, 2007·Der Urologe. Ausg. A·M F HamannP M Braun
Dec 25, 2009·Der Urologe. Ausg. A·O ReichC Stief
Mar 7, 2006·World Journal of Urology·Ehab A Elzayat, Mostafa M Elhilali
Mar 30, 2007·World Journal of Urology·Andrew J Marks, Joel M H Teichman
May 29, 2007·World Journal of Urology·Rainer M Kuntz
Jul 23, 2011·International Urology and Nephrology·Tania A Hossack, Henry H Woo
Jun 28, 2005·Current Urology Reports·Werner W Hochreiter, Roger M Müller
Jun 1, 2005·European Urology·Alexander BachmannTullio Sulser
Feb 13, 2009·International Journal of Impotence Research·J Henning, S Waxman
Feb 14, 2006·Nature Clinical Practice. Urology·Liam C Wilson, Peter J Gilling
Jun 7, 2006·Prostate Cancer and Prostatic Diseases·R C Harkaway, M M Issa
Dec 20, 2005·Journal of Endourology·Jaspreet S SandhuAlexis E Te
Aug 15, 2006·Journal of Endourology·David M Bouchier-HayesAnthony J Costello
Jul 15, 2009·Journal of Endourology·Stephan BuseMarkus Hohenfellner
Sep 25, 2008·Journal of Endourology·Gerasimos Alivizatos, Andreas Skolarikos
Oct 23, 2010·Journal of Endourology·Massimiliano SpalivieroCarson Wong
Jun 1, 2009·Therapeutic Advances in Urology·Doreen E Chung, Alexis E Te
Nov 26, 2009·Patient Preference and Adherence·Jaspreet S Sandhu
Dec 4, 2012·Indian Journal of Urology : IJU : Journal of the Urological Society of India·Nayan K MohantyRajender P Arora
Mar 10, 2009·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·M FourmarierUNKNOWN le Comité des troubles mictionnels de l'homme (CTMH) de l'Association française d'urologie

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