Photoselective vaporization of the prostate using a laser high performance system in the canine model

The Journal of Urology
Richard LeeAlexis E Te

Abstract

Photoselective vaporization of the prostate with the 80 W KTP laser has been shown to be an effective and durable therapy for benign prostatic hyperplasia. We investigated the new, more powerful GreenLight HPS(R) High Performance System laser in the canine model as a more rapid treatment for benign prostatic hyperplasia. Five male beagles underwent general anesthesia and laparotomy. Photoselective vaporization of the prostate was performed in antegrade fashion through a suprapubic cystotomy at 40, 80 and 120 W at 3 firing periods (5, 10 and 20 seconds). Photoselective vaporization of the prostate was performed for each power and time combination in stationary fashion at unique locations. Prostates were harvested and histopathological analysis was performed. Mean vaporization and coagulation depths of each laser setting were determined and compared using ANOVA. Vaporization depth was 4 mm to full thickness. Coagulation occurred 1.2 to 2.5 mm deep to the vaporization zone. Increasing laser power appeared to increase depth of vaporization with equivalent or less coagulation depth and increasing the lasing duration behaved similarly. Microscopic pathological evaluation revealed damage to adjacent tissues in areas of full-thickness ...Continue Reading

References

Jan 1, 1992·Lasers in Surgery and Medicine·D E JohnsonD M Cromeens
Jan 1, 1994·Lasers in Surgery and Medicine·J N Kabalin, H S Gill
May 8, 2000·The Journal of Urology·R S MalekD M Barrett
Dec 20, 2005·Journal of Endourology·Jaspreet S SandhuAlexis E Te

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Citations

Jul 11, 2013·Journal of Endourology·Franck BruyèreLaurent Brunereau
Jul 16, 2010·European Urology·Rocco Damiano, Riccardo Autorino
Nov 28, 2009·The Urologic Clinics of North America·Matthew S Wosnitzer, Matthew P Rutman
Jun 22, 2013·Korean journal of urology·E Charles Osterberg, Benjamin B Choi
Oct 27, 2011·Expert Review of Medical Devices·Bilal Chughtai, Alexis Te

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