Phrasing of the patient global assessment in the rheumatoid arthritis ACR/EULAR remission criteria: an analysis of 967 patients from two databases of early and established rheumatoid arthritis patients

Clinical Rheumatology
Laure GossecRAID investigators

Abstract

The ACR/EULAR Boolean remission criteria for rheumatoid arthritis (RA) include a strict cutoff for patient global assessment (PGA, value ≤ 1/10). Near-remission corresponds to remission for joint counts and C-reactive protein but with PGA > 1. The objective was to explore whether the contribution of PGA to remission and near-remission varied according to the wording of the PGA and in relation to disease duration. In patients with early arthritis (N = 731, French ESPOIR cohort) or established RA (N = 236 patients from across Europe), frequency of remission versus near-remission was assessed according to the phrasing used for PGA (global health versus disease activity). In 967 patients (mean [standard deviation] age 49.7 [12.7] years, 76.7% women), remission was infrequent: range 12.9-16.7% (according to wording of PGA) in early RA and 6.8-7.2% in established RA. Near-remission was more frequent: 13.0-16.8% in early RA and 13.1-13.6% in established RA. The ratio of remission to near-remission was higher in the early arthritis cohort (0.8-1.3 versus 0.5-0.5 in established RA). Using the disease activity PGA led to more remission and less near-remission than the global health PGA in the early arthritis cohort (12.9 vs 16.7% near-re...Continue Reading

References

Apr 3, 2007·Archives of Physical Medicine and Rehabilitation·Carolyn E SchwartzUNKNOWN RRTC Expert Panel on Health Status Measurement
Aug 24, 2012·Annals of the Rheumatic Diseases·Katja ThieleUNKNOWN German Collaborative Arthritis Centres
Feb 14, 2014·Annals of the Rheumatic Diseases·Lilian H D van TuylMaarten Boers
Mar 4, 2014·Journal of Clinical Epidemiology·Maarten BoersPeter Tugwell
Mar 4, 2014·The Journal of Rheumatology·John R KirwanLaure Gossec
Sep 23, 2014·Joint, Bone, Spine : Revue Du Rhumatisme·Bernard Combe, Nathalie Rincheval
May 15, 2015·Annals of the Rheumatic Diseases·Josef S SmolenDesirée van der Heijde
Oct 30, 2016·Arthritis Research & Therapy·Elena NikiphorouLaure Gossec

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Citations

Jun 8, 2021·Therapeutic Advances in Musculoskeletal Disease·Serena BugattiCarlomaurizio Montecucco
Apr 1, 2019·Joint, Bone, Spine : Revue Du Rhumatisme·Jean-Jacques DubostMartin Soubrier

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