Phylogenetic analysis of hepatitis E virus isolates in southern China (1994-1998)

Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
Shaojing WeiShing Shun Tony To

Abstract

We have previously reported the identification of divergent hepatitis E virus (HEV) isolated (G9, G20 and 93G) in Guangzhou, a city in southern China. They are now recognised as a new HEV subgenotype in the world. However, the relatedness and significance of these novel isolates in sporadic HEV infection in southern China is still unclear. To perform phylogenetic analysis of nucleotide sequences from 41 HEV isolates in southern China from 1994 to 1998. The partial nucleotide sequence of the HEV isolates were determined and compared with reported sequences in the GenBank. Their relatedness was analysed using computer software. The majority of the HEV isolates, 39 out of 41, were found to belong to the Burmese-like isolates (genotype 1). The other two belonged to the Guangzhou-like isolates. The latter were only found in the samples collected in 1994. They, together with the G9 isolate, form a unique tree located between genotype 1 and genotype 4 (divergent HEV strains from northern China and Taiwan) on the phylogenetic tree. Our results suggest that the Burmese-like isolates are the main causative agents of sporadic HEV infection in southern China. The Guangzhou-like isolates, which appeared transiently in 1994, did not seem to ...Continue Reading

References

Jan 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·S A TsarevR H Purcell
May 18, 1989·Nature·S Kwok, R Higuchi
Sep 2, 1997·Proceedings of the National Academy of Sciences of the United States of America·X J MengS U Emerson
Jan 4, 1998·Journal of Medical Virology·H van Cuyck-GandréC F Longer
May 15, 1998·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J C WuS D Lee
Dec 5, 1998·The New England Journal of Medicine·H C WormG Frösner
Feb 6, 1999·The Journal of General Virology·Y WangT J Harrison
Mar 24, 1999·Journal of Medical Virology·A R ZanettiI K Mushahwar
Jun 6, 2002·Microbes and Infection·Harald C WormGerald Brandstätter
Nov 1, 2002·The New England Journal of Medicine·Kazuyuki SuzukiHiroaki Okamoto

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Citations

May 1, 2009·Emerging Infectious Diseases·Wai Yip LamPaul K S Chan
Mar 13, 2012·World Journal of Gastroenterology : WJG·Xian-Feng ChengLing-Fei Han
Nov 19, 2013·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Y-H LuY-J Zheng
Oct 22, 2013·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Yansheng GengYouchun Wang
May 10, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·James V ConlanStuart D Blacksell
Mar 25, 2008·Journal of Medical Virology·Weijin HuangYouchun Wang
Nov 29, 2007·Journal of Drug Targeting·Christine VauthierGilles Ponchel
Nov 12, 2019·Vox Sanguinis·Wai-Chiu TsoiJerry Holmberg

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