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Phylogenetic Identification and Functional Characterization of Orthologs and Paralogs across Human, Mouse, Fly, and Worm

bioRxiv

May 31, 2014

Yi-Chieh WuManolis Kellis

Abstract

Model organisms can serve the biological and medical community by enabling the study of conserved gene families and pathways in experimentally-tractable systems. Their use, however, hinges on the ability to reliably identify evolutionary orthologs and paralogs with high accuracy, which ...read more

Mentioned in this Paper

RAD51B gene
Drosophila
Phylogenetic Analysis
Anatomy, Regional
Biochemical Pathway
Species
Gene Duplication Abnormality
Laboratory mice
RAD51C protein, mouse
Study
5
38
Paper Details
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Phylogenetic Identification and Functional Characterization of Orthologs and Paralogs across Human, Mouse, Fly, and Worm

bioRxiv

May 31, 2014

Yi-Chieh WuManolis Kellis

PMID: 990005736

DOI: 10.1101/005736

Abstract

Model organisms can serve the biological and medical community by enabling the study of conserved gene families and pathways in experimentally-tractable systems. Their use, however, hinges on the ability to reliably identify evolutionary orthologs and paralogs with high accuracy, which ...read more

Mentioned in this Paper

RAD51B gene
Drosophila
Phylogenetic Analysis
Anatomy, Regional
Biochemical Pathway
Species
Gene Duplication Abnormality
Laboratory mice
RAD51C protein, mouse
Study
5
38
Paper Details
References
  • References
  • Citations
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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