Nov 20, 2016

Phylosymbiosis: Relationships and Functional Effects of Microbial Communities across Host Evolutionary History

PLoS Biology
Andrew W BrooksSeth R Bordenstein

Abstract

Phylosymbiosis was recently proposed to describe the eco-evolutionary pattern, whereby the ecological relatedness of host-associated microbial communities parallels the phylogeny of related host species. Here, we test the prevalence of phylosymbiosis and its functional significance under highly controlled conditions by characterizing the microbiota of 24 animal species from four different groups (Peromyscus deer mice, Drosophila flies, mosquitoes, and Nasonia wasps), and we reevaluate the phylosymbiotic relationships of seven species of wild hominids. We demonstrate three key findings. First, intraspecific microbiota variation is consistently less than interspecific microbiota variation, and microbiota-based models predict host species origin with high accuracy across the dataset. Interestingly, the age of host clade divergence positively associates with the degree of microbial community distinguishability between species within the host clades, spanning recent host speciation events (~1 million y ago) to more distantly related host genera (~108 million y ago). Second, topological congruence analyses of each group's complete phylogeny and microbiota dendrogram reveal significant degrees of phylosymbiosis, irrespective of host c...Continue Reading

Mentioned in this Paper

Host-Parasite Interactions
Patterns
Mutualism
Histocompatibility Antigens
Hominidae
Drosophila
Peromyscus
Phylogeny
Nasonia
Mice, Deer

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