Physical activity, alcohol consumption, BMI and smoking status before and after prostate cancer diagnosis in the ProtecT trial: opportunities for lifestyle modification

International Journal of Cancer. Journal International Du Cancer
Lucy E Hackshaw-McGeaghProtecT study group

Abstract

Associations between certain lifestyle characteristics and prostate cancer risk have been reported, and continuation post-diagnosis can adversely affect prognosis. We explored whether men make spontaneous changes to their physical activity and alcohol intake, body mass index (BMI) and smoking status, following a diagnosis of localised prostate cancer. A detailed diet, health and lifestyle questionnaire was completed by 511 participants within the Prostate Testing for Cancer and Treatment (ProtecT) randomised controlled trial, both before and 9 months after a diagnosis of prostate cancer. Of 177 men who were insufficiently active before their diagnosis (median 0 activity units/week; IQR 0-9), 40.7% had increased their activity by a median of 22 U week(-1) (IQR 15-35) 9 months later, and there was weak evidence that men were more active after diagnosis than before (p = 0.07). Men categorised as "working" occupational social class and who were insufficiently active before diagnosis were 2.03 (95%, CI = 1.03-3.99, p = 0.04) times more likely to have increased their physical activity levels compared to men classified as "managerial or professional." Similarly, men who were insufficiently active pre-diagnosis and with T-stage 2 compa...Continue Reading

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Citations

Feb 9, 2018·BMC Cancer·Evelyn Jiménez-MendozaLuisa E Torres-Sánchez
May 20, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Jeongmin LeeJustin Y Jeon
Aug 1, 2018·British Journal of Cancer·Luigino Dal MasoJerry Polesel
May 29, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Lawson EngJennifer M Jones
Nov 14, 2019·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Karen SteindorfNadine Ungar
Dec 14, 2018·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Chelsea R StoneChristine M Friedenreich
Dec 3, 2020·Molecular Cancer Research : MCR·Nikunj GevariyaVincent Fradet

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Methods Mentioned

BETA
biopsy

Software Mentioned

ProtecT

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