Physical Activity and Its Association with Insulin Resistance in Multicenter AIDS Cohort Study Men

AIDS Research and Human Retroviruses
Anne K MonroeMichael W Plankey

Abstract

The association between physical activity (PA), degree of insulin resistance (IR), and HIV infection is unclear. We hypothesized that PA might differentially affect the degree of IR through the direct and indirect influences of HIV, antiretroviral medications, and sociodemographic characteristics. The International Physical Activity Questionnaire (IPAQ) was administered to Multicenter AIDS Cohort Study (MACS) participants from 4/2010 to 3/2011 to generate metabolic equivalents (METs) total score and PA category. We determined the concurrent homeostatic model assessment IR (mmol/liter) (HOMA-IR) value from fasting glucose and insulin. We examined the HIV-PA relationship using quantile regression and the HIV-PA-HOMA-IR value relationship using linear regression. Among the 1,281 men, the proportions of men in the low (25% in HIV(+) vs. 23% in HIV(-)), moderate (26% vs. 27%), and high (49% vs. 49%) PA categories were similar by HIV status. The HOMA-IR value was higher among the HIV(+) men (p<0.001), and both HIV infection and low PA were associated with a higher degree of IR (p<0.0001 and p=0.0007). However, the PA-HOMA-IR value interaction was not different by HIV status. The HOMA-IR value was higher among HIV(+) men although the ...Continue Reading

References

Oct 24, 2003·The Journal of the Association of Nurses in AIDS Care : JANAC·Evelyn M Clingerman
Sep 28, 2005·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Clara Y JonesChristine Wanke
May 22, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Paolo BonfantiGiuseppe Mancia
Dec 20, 2007·Medicine and Science in Sports and Exercise·Richard P TroianoMargaret McDowell
Jan 3, 2008·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Carl GrunfeldSteven B Heymsfield
Jul 30, 2008·International Journal of STD & AIDS·S FillipasC L Cherry
Feb 19, 2009·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Katherine Samaras
Feb 2, 2010·The Journal of the Association of Nurses in AIDS Care : JANAC·Soula FillipasCatherine L Cherry
Oct 21, 2010·American Journal of Physiology. Endocrinology and Metabolism·Kevin E YarasheskiDominic N Reeds
Oct 25, 2011·The International Journal of Behavioral Nutrition and Physical Activity·Paul H LeeSunita M Stewart
Nov 5, 2011·Medicine and Science in Sports and Exercise·John J DubéFrancesca Amati
Mar 1, 2012·International Journal of STD & AIDS·L SteinR Beneke
Jul 6, 2012·Current HIV Research·Fabiana Schuelter-TrevisolSandra C Fuchs
Apr 1, 2011·Future Virology·Allison LongenbergerLawrence A Kingsley

❮ Previous
Next ❯

Citations

Feb 26, 2016·Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy·Kathrin Schulte-HermannThomas E Dorner
Dec 9, 2016·Disability and Rehabilitation·Davy VancampfortBrendon Stubbs
Mar 23, 2017·Disability and Rehabilitation·Davy VancampfortBrendon Stubbs
Dec 1, 2017·The Journal of Cardiovascular Nursing·Allison R WebelRichard A Josephson
Aug 20, 2016·Current HIV/AIDS Reports·Amanda L Willig, Edgar Turner Overton

❮ Previous
Next ❯

Methods Mentioned

BETA
ELISA

Software Mentioned

SAS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.