Physical Activity and Risk of Postoperative Delirium

Journal of the American Geriatrics Society
Susie S LeeJoe Verghese

Abstract

Regular physical activity (PA) has been associated with improved cognitive function, but its effect on postoperative delirium (POD) has not been established. Our objectives were to determine the effect of baseline PA on the incidence of POD in older patients undergoing elective orthopedic surgery and to determine whether these effects were independent of cognitive reserve. We hypothesize that PA protects against POD by bolstering physiologic reserve needed to withstand the stressors of surgery. Secondary analysis of a prospective, single-center, cohort study. Urban academic hospital. A total of 132 nondemented, English-speaking adults older than 60 years undergoing elective orthopedic surgery. Subjects were screened for POD and delirium severity using the Confusion Assessment Method and the Memorial Delirium Assessment Scale. Baseline cognitive activities and PAs were assessed with a validated Leisure Activity Scale. Regular PA was categorized as 6 to 7 days per week. The association of regular PA with incidence of POD was assessed using multivariable logistic regression, adjusting for age, sex, Charlson Comorbidity Index, cognitive reserve, and cognitive function. Linear regression was used to assess the association of deliriu...Continue Reading

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Citations

Nov 19, 2020·Alzheimer's & Dementia : Translational Research & Clinical Interventions·Kenneth RockwoodLindsay M K Wallace
Jun 16, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Heleen C van der HulstJan Willem T Dekker

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