Physical Activity and Symptoms in Pulmonary Arterial Hypertension

Chest
Lea Ann MaturaSteven M Kawut

Abstract

Fatigue is a common symptom in patients with pulmonary arterial hypertension (PAH); however, the impact of fatigue on daily physical activity in PAH is unknown. Accelerometry is a validated measure for assessing physical activity. We hypothesized that patients with PAH reporting higher levels of fatigue would have lower daily physical activity measured by accelerometry. We performed a prospective cohort study of 15 women with PAH. On day 1, subjects completed the Multidimensional Fatigue Inventory (MFI), the United States Cambridge Pulmonary Hypertension Outcome Review (US CAMPHOR), and a 6-min walk test. Subjects wore the accelerometer on their dominant hip and completed an activity diary for 7 days. On day 15, subjects repeated the MFI and the US CAMPHOR, and then wore the accelerometer and completed an activity diary for an additional 7 days. All multivariate analyses were adjusted for age, BMI, and PAH type. The mean age was 50.5 years, and 53% had idiopathic or heritable PAH. During the 2 weeks, subjects were mostly sedentary (85% of the time), although 10% of their time was spent performing low-level activity. Lower average daily counts were associated with worse self-reported energy levels, whereas less day-to-day physic...Continue Reading

References

Jan 1, 1985·Journal of Chronic Diseases·G H GuyattS O Pugsley
Apr 1, 1995·Journal of Psychosomatic Research·E M SmetsJ C De Haes
Jan 1, 1993·Medicine and Science in Sports and Exercise·B E AinsworthR S Paffenbarger
Nov 20, 1998·Archives of Physical Medicine and Rehabilitation·R Moe-Nilssen
Feb 13, 2001·Journal of Psychosomatic Research·S P van der WerfG Bleijenberg
Apr 11, 2001·Archives of Physical Medicine and Rehabilitation·V MathiowetzM E Murphy
Oct 2, 2001·American Heart Journal·C DemersUNKNOWN RESOLVD Pilot Study Investigators
May 25, 2002·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Joseph A RoscoePaul L R Andrews
Oct 6, 2005·The European Respiratory Journal·G DeboeckR Naeije
Jul 13, 2006·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Kristin FalkInger Ekman
Mar 6, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Michael A EchteldCarin C D van der Rijt
Jan 12, 2008·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mardi Gomberg-MaitlandStephen P McKenna
May 23, 2008·Medicine and Science in Sports and Exercise·Charles E Matthews
Sep 30, 2010·Disability and Rehabilitation·Nicola M KayesGregory S Kolt
Feb 24, 2012·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Lea Ann MaturaDiane L Carroll
Mar 16, 2012·Medical Engineering & Physics·Alejandro Santos-LozanoNuria Garatachea
Aug 8, 2012·Journal of Affective Disorders·Christopher BurtonMaria Wolters
Nov 16, 2012·The Journal of Cardiovascular Nursing·Lea Ann MaturaDiane L Carroll

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Citations

Jan 25, 2018·Annals of Medicine·Massimo LeggioAndrea Mazza
Jan 11, 2018·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·Kamonwan Tangvoraphonkchai, Andrew Davenport
Nov 14, 2018·Pulmonary Circulation·Stephen J HallidayAnna R Hemnes
Apr 16, 2019·Pulmonary Circulation·Thomas M CascinoElizabeth A Jackson
Feb 20, 2020·Expert Opinion on Drug Delivery·Ali KeshavarzFakhrul Ahsan
May 27, 2020·American Journal of Respiratory Cell and Molecular Biology·M Patricia GeorgeBrian B Graham
Jun 4, 2020·Pulmonary Circulation·Karen S W ChiaChristine T Shiner
Mar 19, 2019·The European Respiratory Journal·Thomas M CascinoElizabeth A Jackson
May 5, 2020·Pulmonary Circulation·Shelley ShapiroAndrew C Nelsen
May 13, 2019·Clinics in Chest Medicine·James R VallerandPierantonio Laveneziana
May 3, 2019·Respiratory Medicine·Sameep SehgalKristin B Highland
Jun 16, 2021·Current Opinion in Pulmonary Medicine·Allyson L Hughes, Anna R Hemnes
Aug 11, 2021·American Journal of Respiratory and Critical Care Medicine·Jennifer Marvin-PeekEvan L Brittain

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