Physical activity energy expenditure vs cardiorespiratory fitness level in impaired glucose metabolism

Diabetologia
Lærke P LidegaardKristine Færch

Abstract

Little is known about the relative roles of physical activity energy expenditure (PAEE) and cardiorespiratory fitness (CRF) as determinants of glucose regulation. The aim of this study was to examine the associations of PAEE and CRF with markers of glucose metabolism, and to test the hypothesis that CRF modifies the association between PAEE and glucose metabolism. We analysed cross-sectional data from 755 adults from the Danish ADDITION-PRO study. On the basis of OGTT results, participants without known diabetes were classified as having normal glucose tolerance, isolated impaired fasting glycaemia (i-IFG), isolated impaired glucose tolerance (i-IGT), combined IFG + IGT or screen-detected diabetes mellitus. Markers of insulin sensitivity and beta cell function were determined. PAEE was measured using a combined heart rate and movement sensor. CRF (maximal oxygen uptake) was estimated using a submaximal 8 min step test. The associations were examined by linear regression analysis. Results were adjusted for relevant confounders. PAEE and CRF were reduced in individuals with i-IGT, combined IFG + IGT and screen-detected diabetes mellitus, but were not significantly different in individuals with i-IFG compared with those with norma...Continue Reading

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Citations

Oct 25, 2016·Medicine and Science in Sports and Exercise·Chip P RowanVeronica K Jamnik
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Nov 30, 2018·Frontiers in Physiology·Rodrigo S DelevattiLuiz Fernando M Kruel
Oct 4, 2017·The Journal of Clinical Endocrinology and Metabolism·Kristine FærchDorte Vistisen

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