Abstract
Intravenous antibiotic therapy (IVAT) for CF acute pulmonary exacerbations (APE) can be delivered in hospital or in the community. This study aimed to compare physical activity in CF patients receiving hospital and community-delivered IVAT, as well as other health outcomes. This was a non-randomised parallel group prospective observational study. Hospitalised and community-treated CF adults receiving IVAT for APE were asked to wear ActiGraph® activity monitors, complete the habitual activity estimation scale (HAES), food diary, modified shuttle test (MST) and CFQ-R at the start and end of therapy. Nutritional and clinical outcomes were also compared between the cohorts. The primary outcomes was physical activity measured by the ActiGraph® activity monitors at the beginning and end of treatment in both cohorts. Physical activity (measured and self-reported) was no different between the cohorts, with both hospitalised and community-treated subjects being generally sedentary. Body weight increased significantly in the hospitalised cohort, whereas no difference was seen in the community-treated cohort. FEV1 % predicted and FVC % predicted increased in community-treated subjects, whereas only FVC % predicted increased in hospitalise...Continue Reading
References
May 1, 1988·Archives of Disease in Childhood·J GilbertJ M Littlewood
Sep 1, 1994·The European Respiratory Journal·M N PondS P Conway
Apr 7, 1999·The Journal of Infectious Diseases·A HolmesR Goldstein
Apr 22, 1999·Thorax·J BradleyS Elborn
Feb 12, 2002·Pediatric Pulmonology·H C SelvaduraiP P Van Asperen
Dec 13, 2002·Infection·J RiethmuellerM Stern
Jan 22, 2004·Chest·James R YankaskasDavid Rodman
Feb 27, 2004·Thorax·J ThorntonA K Webb
Mar 6, 2004·The Journal of Infection·J M WolterJ G McCormack
Nov 26, 2004·Thorax·A J MoorcroftA K Webb
Mar 9, 2005·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Eitan KeremUNKNOWN Consensus Committee
Oct 26, 2005·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·J ThorntonA K Webb
Jan 5, 2006·Journal of Clinical Nursing·Glenda EsmondAnne Marie McCormack
Jun 17, 2006·Pediatric Pulmonology·Dena NazerSara Pendleton
Feb 29, 2008·Pediatric Pulmonology·Greg D WellsAllan L Coates
Aug 6, 2008·Pediatric Pulmonology·A TermozI Durieu
May 19, 2009·Chest·Alexandra L QuittnerA Bruce Montgomery
Jul 31, 2009·Annals of Thoracic Medicine·Iara Maria Sequeiros, Nabil A Jarad
Aug 1, 2009·The European Respiratory Journal·H HebestreitS Kriemler
Jun 29, 2010·American Journal of Respiratory and Critical Care Medicine·J Michael CollacoPeter J Mogayzel
Sep 11, 2010·Chest·Tiffany J DwyerPeter T P Bye
Dec 2, 2011·Medical Science Monitor : International Medical Journal of Experimental and Clinical Research·Moran LavieOri Efrati
Jan 12, 2012·BMC Medical Research Methodology·Niels SmitsIngrid V E Carlier
Apr 23, 2013·Respiratory Medicine·Nathan WardThomas Sullivan