Physical activity in relation to total, advanced, and fatal prostate cancer.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology
Steven C MooreMichael F Leitzmann

Abstract

Physical activity has been inconsistently related to total prostate cancer and few studies have examined whether this association varies by disease aggressiveness. We examined physical activity in relation to total, advanced, and fatal prostate cancer in the NIH-AARP Diet and Health Study. At baseline (1995-1996), 293,902 men ages 50 to 71 years completed a questionnaire inquiring about current frequency of vigorous exercise of at least 20 min of duration, as well as frequency of exercise during adolescence (ages 15-18). We used proportional hazards regression to calculate multivariate relative risks (RR) and 95% confidence intervals (95% CI). During up to 8.2 years of follow-up, 17,872 prostate cancer cases were identified, including 1,942 advanced and 513 fatal cases. Comparing frequent (5+ times per week) versus infrequent (less than once per week) vigorous exercise, exercise at baseline was not associated with risk of total prostate cancer (RR, 1.01; 95% CI, 0.96-1.07; P(trend) = 0.78), advanced prostate cancer (RR, 1.14; 95% CI, 0.97-1.33; P(trend) = 0.25), or fatal prostate cancer (RR, 0.90; 95% CI, 0.67-1.20; P(trend) = 0.12). Increasing level of vigorous exercise during adolescence was associated with a small 3% reducti...Continue Reading

References

Jan 1, 1987·The American Journal of Clinical Nutrition·J E VenaM K Swanson
May 23, 2001·International Journal of Epidemiology·J V LaceyA W Hsing
Jun 21, 2001·Biochemical and Biophysical Research Communications·H QianC A Baile
Sep 8, 2001·Cancer Causes & Control : CCC·C M Friedenreich, I Thune
Mar 19, 2003·Lancet·Henrik Grönberg
Jun 26, 2003·The New England Journal of Medicine·Ian M ThompsonCharles A Coltman
Jan 8, 2004·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·E Giovannucci
Mar 31, 2004·American Journal of Epidemiology·C M FriedenreichF G Elliott
Dec 21, 2004·International Journal of Cancer. Journal International Du Cancer·Barbara PierottiCarlo La Vecchia
Feb 16, 2005·The Journal of Urology·Paul F PinskyUNKNOWN Prostate, Lung, Colorectal and Ovarian Project Team
Mar 29, 2005·European Journal of Epidemiology·Le JianColin W Binns
Apr 26, 2005·British Journal of Sports Medicine·A L MarshallS Kaur
May 11, 2005·Archives of Internal Medicine·Edward L GiovannucciWalter C Willett
Jun 9, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Maurice P A ZeegersPiet A van den Brandt
Oct 6, 2005·British Journal of Cancer·Y C ChenF-C Sung
Jun 20, 2006·Cancer Causes & Control : CCC·Alyson J LittmanEmily White
Oct 5, 2006·International Journal of Cancer. Journal International Du Cancer·Tom I L NilsenLars J Vatten
Apr 24, 2007·International Journal of Cancer. Journal International Du Cancer·Edward GiovannucciWalter C Willett
Jan 31, 2008·Journal of the National Cancer Institute·UNKNOWN Endogenous Hormones and Prostate Cancer Collaborative GroupTimothy J Key
Feb 1, 2008·Nature Reviews. Cancer·Anne McTiernan

❮ Previous
Next ❯

Citations

Oct 16, 2012·Wiener medizinische Wochenschrift·Hans-Christian Heitkamp, Ivan Jelas
Nov 30, 2010·Cancer Causes & Control : CCC·Hosanna Soler-ViláBeth A Jones
Apr 5, 2011·Cancer Causes & Control : CCC·Brooke M WinzerJennifer D Paratz
Apr 17, 2012·Asian Journal of Andrology·Kathryn M WilsonLorelei A Mucci
Mar 11, 2009·Prostate Cancer and Prostatic Diseases·J AntonelliL W Jones
Nov 20, 2009·The Aging Male : the Official Journal of the International Society for the Study of the Aging Male·Halina GrosmanGabriela Berg
Oct 2, 2012·Urologic Oncology·Kathleen Y Wolin, Carolyn Stoll
Oct 30, 2010·Cancer Epidemiology·Marie-Élise ParentJack Siemiatycki
Sep 17, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Christine M FriedenreichBrigid M Lynch
Sep 18, 2009·The Journal of Urology·Jodi A AntonelliStephen J Freedland
Jan 6, 2015·World Journal of Urology·Alessandra GrottaYlva Trolle Lagerros
Sep 3, 2013·Asian Pacific Journal of Cancer Prevention : APJCP·Joanna Kruk, Urszula Czerniak
Oct 22, 2008·European Journal of Epidemiology·Fredrik WiklundHenrik Grönberg
Dec 27, 2011·World Journal of Urology·Stacey Young-McCaughan
Jul 25, 2019·European Journal of Cancer Care·Sarah WellerKristin L Campbell
Nov 16, 2016·Sports Medicine·Roy J Shephard
Jul 15, 2015·Cancer Prevention Research·Soffia M HrafnkelsdóttirUnnur A Valdimarsdóttir
Feb 15, 2014·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Brigid M LynchCharles E Matthews
May 23, 2018·Annals of Oncology : Official Journal of the European Society for Medical Oncology·I N BenkeD Schmid

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.