Physical activity, obesity, and cognitive impairment among women with systemic lupus erythematosus.

Arthritis Care & Research
Patricia KatzLindsey A Criswell

Abstract

To examine relationships of obesity and physical inactivity to cognitive impairment in women with systemic lupus erythematosus (SLE). Body composition was measured with dual x-ray absorptiometry (DXA) for 138 women with SLE. Obesity was defined by total percent body fat. Physical activity was ascertained with the self-reported International Physical Activity Questionnaire; inactivity was defined as expenditure of <600 metabolic equivalent minutes/week. Cognitive function was assessed with a 12-index neuropsychological battery. Impairment was defined as age-adjusted Z scores ≤1.5 SDs below the mean on 1 of 3 of tests completed. Scores were obtained for the total battery and for memory and executive function components. Multivariate analyses examined the relationship of obesity and physical activity, individually and combined, to cognitive impairment, controlling for education, race/ethnicity, disease activity, glucocorticoid use, and depression. Fifteen percent of subjects were cognitively impaired, 28% were physically inactive, and 50% were obese. Five percent of active women were impaired on the executive function battery compared to 23% of those who were inactive (P = 0.003). Obese women were more likely to be impaired on the...Continue Reading

References

Jan 1, 1992·Rheumatology International·A KumarR Kakkar
Nov 1, 1992·The American Journal of Medicine·M PetriM C Hochberg
Jun 1, 1986·The Journal of Nervous and Mental Disease·R M CarbotteJ A Denburg
Apr 1, 1997·British Journal of Rheumatology·R WesthovensJ Dequeker
Jul 3, 1998·British Journal of Rheumatology·Y KipenE F Morand
Sep 1, 2000·The American Journal of Clinical Nutrition·D GallagherY Sakamoto
Feb 7, 2001·American Journal of Epidemiology·D F GeffkenR P Tracy
Jul 19, 2001·Journal of the International Neuropsychological Society : JINS·J V BaldoE Kaplan
Sep 29, 2001·Journal of the International Neuropsychological Society : JINS·E KozoraS G West
Oct 30, 2001·The Proceedings of the Nutrition Society·S W Coppack
Jun 1, 2002·Archives of Internal Medicine·Jerome L Abramson, Viola Vaccarino
Oct 18, 2002·Arthritis and Rheumatism·Laura C RallRonenn Roubenoff
Aug 2, 2003·Journal of the American Geriatrics Society·David B ReubenUNKNOWN MacArthur Studies of Successful Aging
Aug 6, 2003·Medicine and Science in Sports and Exercise·Cora L CraigPekka Oja
Jun 24, 2004·Journal of the American Geriatrics Society·Lisa H ColbertTamara B Harris
Sep 15, 2004·Journal of Science and Medicine in Sport·W J BrownN Owen
Sep 24, 2004·JAMA : the Journal of the American Medical Association·Jennifer WeuveFrancine Grodstein
Nov 13, 2004·JAMA : the Journal of the American Medical Association·Kristine YaffeAnne B Newman
Sep 10, 2005·Annals of the Rheumatic Diseases·M M FreemerL A Criswell
May 26, 2006·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·John GunstadRonald A Cohen
Aug 24, 2006·Public Health Nutrition·Maria HagströmerMichael Sjöström
Dec 6, 2006·Comprehensive Psychiatry·John GunstadEvian Gordon
Feb 3, 2007·Arthritis and Rheumatism·Edward YelinPeter Panopalis
May 12, 2007·Journal of the American Geriatrics Society·Snorri B RafnssonF Gerald R Fowkes
Sep 1, 2007·Medicine and Science in Sports and Exercise·Walter R BixbyBradley D Hatfield
Jan 1, 2008·Arthritis and Rheumatism·Jinoos YazdanyPatricia P Katz
Jan 24, 2008·Circulation·Ralph B D'AgostinoWilliam B Kannel
Mar 25, 2008·Neurobiology of Aging·Karen F HoldenUNKNOWN Health ABC study
Aug 5, 2008·Brain Research·John GunstadJudi Juvancic-Heltzel
Sep 6, 2008·Journal of the American Geriatrics Society·Karin F HothRonald A Cohen

❮ Previous
Next ❯

Citations

Jul 10, 2013·Current Opinion in Rheumatology·Antonis FanouriakisGeorge K Bertsias
Jul 23, 2014·Arthritis Care & Research·James S AndrewsPatricia P Katz
Oct 2, 2014·Autonomic & Autacoid Pharmacology·P J Fitzgerald
Sep 25, 2014·Arthritis Care & Research·Grace E AhnRosalind Ramsey-Goldman
Sep 25, 2015·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Catherine QuinlanKjell Tullus
Jan 28, 2015·Arthritis Care & Research·James S AndrewsPatricia P Katz
May 24, 2015·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Catherine QuinlanKjell Tullus
Sep 7, 2016·Pediatric Rheumatology Online Journal·Sangeeta Sule, Kevin Fontaine
Mar 1, 2017·Lupus Science & Medicine·Patricia P KatzEdward Yelin
Apr 16, 2019·Obesity·María Arnoriaga RodríguezJosé Manuel Fernández-Real
Apr 28, 2019·Lupus·G A RobinsonE C Jury
May 17, 2019·Expert Review of Clinical Immunology·Chi Chiu Mok
Sep 27, 2018·Current Rheumatology Reviews·Andrew KwanZahi Touma
Jan 11, 2020·Frontiers in Psychology·Terence A MoriartyMicah Zuhl
Jun 2, 2020·Annals of the Rheumatic Diseases·Alexis Mathian, Zahir Amoura
Apr 19, 2018·The Journal of Physiological Sciences : JPS·Paul D Loprinzi, Emily Frith

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.