journal cover

Physical confinement alters sarcoma cell cycle progression and division

Cell Cycle

Oct 12, 2018

Rebecca A Moriarty, Kimberly M Stroka

Abstract

Tumor cells experience physical confinement on one or multiple axes, both in the primary tumor and at multiple stages during metastasis. Recent work has shown that confinement in a 3D spheroid alters nucleus geometry and delays cell division, and that vertical confinement impairs mitoti...read more

Mentioned in this Paper

Cell Cycle Progression
Tumor Cells, Uncertain Whether Benign or Malignant
Sarcoma
Size
Coating Excipient
Cell Motility
Neoplastic Cell
Mitotic Spindle Apparatus
Science of Morphology
Primary Neoplasm
Paper Details
References
  • References44
  • Citations2
12345

Physical confinement alters sarcoma cell cycle progression and division

Cell Cycle

Oct 12, 2018

Rebecca A Moriarty, Kimberly M Stroka

PMID: 30304981

DOI: 10.1080/15384101.2018.1533776

Abstract

Tumor cells experience physical confinement on one or multiple axes, both in the primary tumor and at multiple stages during metastasis. Recent work has shown that confinement in a 3D spheroid alters nucleus geometry and delays cell division, and that vertical confinement impairs mitoti...read more

Mentioned in this Paper

Cell Cycle Progression
Tumor Cells, Uncertain Whether Benign or Malignant
Sarcoma
Size
Coating Excipient
Cell Motility
Neoplastic Cell
Mitotic Spindle Apparatus
Science of Morphology
Primary Neoplasm

Related Papers

Paper Details
References
  • References44
  • Citations2
12345
/papers/physical-confinement-alters-sarcoma-cell-cycle/30304981