Nov 20, 2015

Physical Effects of Buckwheat Extract on Biological Membrane In Vitro and Its Protective Properties

The Journal of Membrane Biology
Aleksandra WłochHalina Kleszczyńska

Abstract

Buckwheat is a valuable source of many biologically active compounds and nutrients. It has properties that reduce blood cholesterol levels, and so reduces the risk of atherosclerosis, seals the capillaries, and lowers blood pressure. The aim of the study was to determine quantitative and qualitative characteristics of polyphenols contained in extracts from buckwheat husks and stalks, the biological activity of the extracts, and biophysical effects of their interaction with the erythrocyte membrane, treated as a model of the cell. An analysis of the extract's composition has shown that buckwheat husk and stalk extracts are a rich source of polyphenolic compounds, the stalk extracts showing more compounds than the husk extract. The study allowed to determine the location which incorporated polyphenols occupy in the erythrocyte membrane and changes in the membrane properties caused by them. It was found that the extracts do not induce hemolysis of red blood cells, causing an increase in osmotic resistance of erythrocytes. They affect mainly the hydrophilic region by changing the degree of order of the polar heads of lipids, but do little to change the fluidity of the membrane and its hydration. The results showed also that polyphe...Continue Reading

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References

Mentioned in this Paper

Biological Membrane
Study
Phocidae
Tissue Membrane
Membrane
Analgesics, Anti-Inflammatory
Polygonaceae
Anti-Inflammatory Agents
Antioxidant Effect
Red blood cells, blood product

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