Physical exercise interventions have no effect on serum BDNF concentration in older adults living in long-term nursing homes.

Experimental Gerontology
Chloe Rezola-PardoJon Irazusta

Abstract

Physical exercise protects against age-related cognitive decline. Brain-derived neurotrophic factor (BDNF) may mediate some of the cognitive benefits of physical exercise, but the effect of physical exercise on serum BDNF is unclear. Indeed, differential findings have been reported depending on the characteristics of the participants and the intensity, duration, and type of exercise. The aim of this study was to determine whether three different physical exercise interventions alter serum BDNF levels in older adults living in long-term nursing homes (LTNHs) and whether changes in physical, cognitive, and dual-task performance are related to changes in serum BDNF. LTNH study participants (n = 126) were randomly assigned to multicomponent or dual-task training or a walking program and serum BDNF levels were analyzed by ELISA. We also assessed physical, cognitive, and dual-task parameters. Neither the multicomponent, dual-task, nor walking exercise programs caused changes in serum BDNF concentration in older adults living in LTNHs. Changes in BDNF during the interventions were not significantly associated with modifications in physical, cognitive or dual-task performance parameters. Our results provide new evidence clarifying the ...Continue Reading

References

Jan 1, 1988·International Disability Studies·D T Wade, C Collin
Oct 8, 1988·BMJ : British Medical Journal·D GoldbergD Grayson
Aug 1, 1996·The Journal of Orthopaedic and Sports Physical Therapy·R W BohannonM W Thomas
May 22, 2002·Psychosomatic Medicine·Rebecca G LogsdonLinda Teri
Dec 9, 2004·Neurobiology of Aging·Marek LommatzschJohann Christian Virchow
Nov 3, 2005·Neurorehabilitation and Neural Repair·Shoshanna Vaynman, Fernando Gomez-Pinilla
May 23, 2006·Gene Expression Patterns : GEP·M J WebsterC Shannon Weickert
Aug 2, 2006·Neurobiology of Aging·Andreas A ZiegenhornRainer Hellweg
Apr 7, 2007·Medicine and Science in Sports and Exercise·Lee T FerrisChwan-Li Shen
Nov 1, 2008·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·T SchifferH K Strüder
Mar 4, 2009·Archives of Physical Medicine and Rehabilitation·Patima SilsupadolMarjorie H Woollacott
Feb 2, 2011·Proceedings of the National Academy of Sciences of the United States of America·Kirk I EricksonArthur F Kramer
Sep 1, 2011·Mayo Clinic Proceedings·J Eric AhlskogRonald C Petersen
Jul 4, 2012·Archives of Gerontology and Geriatrics·Flávia Gomes de Melo CoelhoRuth Ferreira Santos-Galduróz
Jul 4, 2012·Neurobiology of Disease·Karlie A Intlekofer, Carl W Cotman
Dec 5, 2012·Journal of Aging Research·Prudence Plummer-D'AmatoErin Furey
Apr 23, 2013·Scandinavian Journal of Medicine & Science in Sports·T HuangL B Andersen
Oct 30, 2013·Journal of Alzheimer's Disease : JAD·Flávia Gomes de Melo CoelhoRuth Ferreira Santos-Galduróz
May 17, 2014·Journal of Strength and Conditioning Research·Maren S FragalaJay R Hoffman
Jan 8, 2015·Frontiers in Human Neuroscience·Regina L LeckieKirk I Erickson
May 12, 2015·BioMed Research International·Tara L McIsaacLisa M Muratori
Jun 23, 2016·Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Médicas E Biológicas·A Zembron-LacnyM Woźniewski
Apr 26, 2017·British Journal of Sports Medicine·Joseph Michael NortheyBen Rattray
Jun 8, 2017·Ageing Research Reviews·Mikel López Sáez de AsteasuMikel Izquierdo
Jun 8, 2017·Frontiers in Neurology·Sergio ChieffiMarcellino Monda
Jun 18, 2017·Cellular and Molecular Neurobiology·Przemysław KowiańskiJanusz Moryś
Sep 28, 2017·American Journal of Alzheimer's Disease and Other Dementias·Arsalan DamirchiParvin Babaei
May 31, 2018·European Journal of Sport Science·Toshiaki MiyamotoHiroyuki Fujioka

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.