Physical frailty and body composition in obese elderly men and women

Obesity Research
Dennis T VillarealSamuel Klein

Abstract

To evaluate the prevalence of frailty and interrelationships among body composition, physical function, and quality of life in community-dwelling obese elderly (OE) persons. Fifty-two OE, 52 nonobese frail, and 52 nonobese nonfrail subjects, matched for age and sex, were studied. Subjective and objective measures of functional status were evaluated by using the physical performance test, exercise stress test, lower extremity (LE) strength, gait speed, static and dynamic balance, functional status questionnaires, and health-related quality-of-life questionnaire (Medical Outcomes Short Form). Body composition was evaluated by using DXA, and muscle quality was evaluated by determining the ratio of LE strength to LE lean mass. Among OE subjects, 96% met our standard criteria for mild to moderate frailty. Compared with the nonobese nonfrail group, the OE and nonobese frail groups had lower and similar scores in physical performance test, peak aerobic power, and functional status questionnaire, and exhibited similar impairments in strength, walking speed, balance, and health-related quality of life. Although absolute fat-free mass (FFM) was greater, the percentage body weight as FFM and muscle quality was lower in the OE group than i...Continue Reading

References

Nov 1, 1991·Journal of Applied Physiology·W M KohrtJ O Holloszy
Jun 1, 1991·Aging : Clinical and Experimental Research·M Brown, J O Holloszy
Oct 1, 1990·Journal of the American Geriatrics Society·D B Reuben, A L Siu
Aug 1, 1990·The American Journal of Clinical Nutrition·S B HeymsfieldR N Pierson
Dec 1, 1987·Physical Therapy·A M Jette, P D Cleary
Nov 1, 1995·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·C Dutta, E C Hadley
Jun 1, 1995·Journal of Applied Physiology·D N ProctorP W Lemon
Apr 1, 1994·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·L B JensenO H Sørensen
Nov 1, 1993·Journal of Applied Physiology·A R CogganP M Robitaille
Mar 1, 1996·Journal of Applied Physiology·Z M WangS B Heymsfield
Jul 1, 1997·Journal of Applied Physiology·D GallagherS B Heymsfield
Apr 29, 1998·American Journal of Epidemiology·R N BaumgartnerR D Lindeman
May 23, 1998·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·M VisserD P Kiel
Nov 7, 1998·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·E H CoakleyG A Colditz
Jun 11, 1999·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·E J MetterB Hurley
Sep 16, 1999·Medicine and Science in Sports and Exercise·W J KraemerW J Sebastianelli
Jun 8, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·M BrownW M Kohrt
Oct 21, 2000·European Journal of Clinical Nutrition·B Beaufrère, B Morio
Jan 10, 2001·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·L B JensenO H Sørensen
May 18, 2001·Journal of Applied Physiology·B H GoodpasterA B Newman
Aug 22, 2001·JAMA : the Journal of the American Medical Association·D T VillarealW M Kohrt
Sep 14, 2001·Metabolism: Clinical and Experimental·G MingroneA V Greco
Sep 18, 2001·JAMA : the Journal of the American Medical Association·A H MokdadJ P Koplan
Jul 18, 2002·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·R L KolotkinG R Williams
Aug 16, 2002·Obesity Research·Claire A ZizzaBarry M Popkin
Nov 2, 2002·Journal of the American Geriatrics Society·Kirsten Krahnstoever DavisonWilliam H Dietz
Dec 11, 2002·Journal of the American Geriatrics Society·Ellen F BinderJohn O Holloszy
Feb 18, 2003·Journal of the American Geriatrics Society·Anne B NewmanUNKNOWN Health Aging And Body Composition Research Group
Jul 2, 2003·Journal of the American Geriatrics Society·Dennis T VillarealWendy M Kohrt

❮ Previous
Next ❯

Citations

Jan 10, 2013·The Journal of Nutrition, Health & Aging·D L WatersD T Villareal
Mar 9, 2010·The British Journal of Nutrition·Thomas E DornerChristoph Gisinger
Mar 14, 2012·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J E DecariaR J Petrella
Apr 1, 2011·The New England Journal of Medicine·Dennis T VillarealKrupa Shah
Nov 15, 2013·Journal of Nutrition in Gerontology and Geriatrics·Amy EllisJeannine Lawrence
Feb 3, 2009·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Matteo CesariLuigi Ferrucci
Sep 13, 2012·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Mary Elizabeth Bowen
Oct 24, 2008·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Liza MakowskiDeborah M Muoio
Jul 12, 2012·Evidence-based Medicine·Krupa Shah, Dennis T Villareal
Jul 17, 2013·BMC Musculoskeletal Disorders·Stephen P MessierRichard F Loeser
Mar 28, 2008·The Journal of Clinical Endocrinology and Metabolism·Dennis T VillarealSamuel Klein
Sep 25, 2008·The Journal of Clinical Endocrinology and Metabolism·Catherine M JankowskiWendy M Kohrt
Jun 27, 2008·Medicine and Science in Sports and Exercise·Tiffany N FrimelDennis T Villareal
Jan 17, 2012·Medicine and Science in Sports and Exercise·Gordon I SmithBettina Mittendorfer
Dec 15, 2011·Journal of Geriatric Physical Therapy·Ericka N MerriwetherDavid R Sinacore
Dec 29, 2012·Clinical Interventions in Aging·Danilo Sales BocaliniFrancisco Luciano Pontes
Feb 23, 2013·Clinical Interventions in Aging·Lauren M RossenMichael G Perri
Jan 16, 2010·American Journal of Health Promotion : AJHP·Hongdao MengGerald M Eggert
Jul 4, 2012·American Journal of Health Promotion : AJHP·Mary Elizabeth Bowen
Mar 24, 2009·Annales de cardiologie et d'angéiologie·P-H DucluzeauP-L Prost
Jul 31, 2013·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·R Armamento-VillarealD T Villareal
Apr 1, 2014·Archives of Gerontology and Geriatrics·Julio Fernández-GarridoOmar Cauli
Mar 29, 2014·The Journal of Nutrition, Health & Aging·A O BradyE M Evans
Mar 19, 2014·Archives of Gerontology and Geriatrics·Karla Helena Coelho VilaçaJulio Cesar Moriguti
Oct 26, 2013·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Hui ChangJamie A Cooper
Jan 13, 2012·The Journal of Nutrition, Health & Aging·L M DoniniWm C Chumlea
Aug 5, 2014·Applied Ergonomics·Ranjana K Mehta, Lora A Cavuoto
Sep 6, 2007·Canadian Journal of Dietetic Practice and Research : a Publication of Dietitians of Canada = Revue Canadienne De La Pratique Et De La Recherche En Diététique : Une Publication Des Diététistes Du Canada·Dawna Royall
Jul 11, 2008·The Journal of Nutrition, Health & Aging·Y RollandB Vellas
Jan 2, 2008·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Danielle R BouchardMartin Brochu
Jun 16, 2011·American Journal of Epidemiology·Noor HeimMarjolein Visser
Mar 16, 2012·Age and Ageing·Sunghoon ShinJacob J Sosnoff
May 14, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D L WatersA Goulding
May 17, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D S DomicianoR M R Pereira
Jul 11, 2008·The Journal of Nutrition, Health & Aging·S L Miller, R R Wolfe
Oct 5, 2011·The Journal of Nutrition, Health & Aging·M E Canon, E M Crimmins
Nov 8, 2012·The Journal of Nutrition, Health & Aging·M L AspM A Belury

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine
Jacob D KuyvenhovenAmy Piepsz
Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
Sanaullah JanShad Mohammad
© 2022 Meta ULC. All rights reserved