Physical functioning, pain and quality of life after amputation for musculoskeletal tumours: a national survey

The Bone & Joint Journal
S FurtadoC H Gerrand

Abstract

Patients who have limb amputation for musculoskeletal tumours are a rare group of cancer survivors. This was a prospective cross-sectional survey of patients from five specialist centres for sarcoma surgery in England. Physical function, pain and quality of life (QOL) outcomes were collected after lower extremity amputation for bone or soft-tissue tumours to evaluate the survivorship experience and inform service provision. Of 250 patients, 105 (42%) responded between September 2012 and June 2013. From these, completed questionnaires were received from 100 patients with a mean age of 53.6 years (19 to 91). In total 60 (62%) were male and 37 (38%) were female (three not specified). The diagnosis was primary bone sarcoma in 63 and soft-tissue tumour in 37. A total of 20 tumours were located in the hip or pelvis, 31 above the knee, 32 between the knee and ankle and 17 in the ankle or foot. In total 22 had hemipelvectomy, nine hip disarticulation, 35 transfemoral amputation, one knee disarticulation, 30 transtibial amputation, two toe amputations and one rotationplasty. The Toronto Extremity Salvage Score (TESS) differed by amputation level, with poorer scores at higher levels (p < 0.001). Many reported significant pain. In additio...Continue Reading

References

Dec 1, 1995·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·B R FerrellM Grant
Oct 1, 1996·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·A M DavisR S Bell
Jun 4, 2008·The Journal of Bone and Joint Surgery. American Volume·L M JeysA Abudu
Jun 10, 2008·The Journal of Bone and Joint Surgery. British Volume·L H AksnesK S Hall
Feb 11, 2009·World Journal of Surgical Oncology·Adrien DaigelerHans-Ulrich Steinau
Oct 20, 2012·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·C A StillerUNKNOWN RARECARE Working Group
Jan 12, 2013·The Bone & Joint Journal·R J GrimerL Jeys
Apr 29, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·T Ng Kee KwongC Gerrand

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Citations

Jul 2, 2016·The Bone & Joint Journal·F S Haddad
Jul 8, 2016·Disability and Rehabilitation·Sherron FurtadoCraig Gerrand
Aug 21, 2016·The Surgical Clinics of North America·Christina J GutowskiJohn A Abraham
Nov 12, 2016·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·S FurtadoC Gerrand
Dec 22, 2016·The Journal of Bone and Joint Surgery. American Volume·Christian M Ogilvie, Edward Y Cheng
Dec 31, 2016·Pain Practice : the Official Journal of World Institute of Pain·Ryan R Ramsook, David Spinner
May 27, 2017·Annals of Surgical Oncology·Henry G SmithDirk C Strauss
Jun 21, 2017·EFORT Open Reviews·E MascardA Gomez-Brouchet
Sep 28, 2018·Journal of Surgical Oncology·Lauren M Mioton, Gregory A Dumanian
Mar 9, 2019·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·J Jakob, J Schmolders
Jan 5, 2019·Journal of Pediatric Orthopedics·Jessica McQuerryRyan Muchow
Mar 27, 2019·Sarcoma·Lesley StoreyRachel M Taylor
Jun 29, 2017·Arquivos de neuro-psiquiatria·Roberto André Torres de VasconcelosMarcus André Acioly
Oct 27, 2018·Military Medical Research·Elahe FarajiMajid Moudi
Nov 3, 2020·The Bone & Joint Journal·Andrea SambriMassimiliano De Paolis
Sep 30, 2019·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Chiao Yee LimMitsuru Takahashi
Feb 13, 2021·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Tina L DoshiSrinivasa N Raja
Mar 2, 2021·The Bone & Joint Journal·Maria Anna SmolleGerhard Martin Hobusch
Aug 15, 2021·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Sophie J M ReijersWinan J van Houdt
Aug 17, 2021·Disaster Medicine and Public Health Preparedness·Qian WangMan-Sang Wong

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