Physical manoeuvers as a preventive intervention to manage vasovagal syncope: A systematic review

PloS One
Kim DockxPhilippe Vandekerckhove

Abstract

To summarize the best available evidence on the effectiveness of physical counterpressure manoeuvers (PCM) for vasovagal syncope management compared to a control intervention. Control interventions included either a PCM, no intervention, or other interventions feasible in a lay setting. A systematic literature search (March 21st 2018) was performed in the Cochrane Central Register of Controlled Trials, MEDLINE, and Embase. PCM were subdivided into 1) PCM decreasing orthostatic load (PCMOL), 2) PCM shortening the hydrostatic column between heart and brain (PCMHC), 3) PCM using mechanical compression of the veins (PCMMC). The primary outcome was syncope, secondary outcomes included systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), heart rate (HR), stroke volume (SV), cardiac output (CO), and total peripheral resistance (TPR). When possible, a random effects meta-analysis was performed. Odds ratios (OR) with 95% confidence intervals (CI) were calculated for dichotomous outcomes, and mean differences (MD) or standardized mean differences (SMD) were calculated for continuous outcomes. Heterogeneity was assessed by means of the I2 statistic. The total body of evidence was evaluated by means ...Continue Reading

References

Feb 1, 1993·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·W WielingA M van Leeuwen
Dec 24, 1997·Annals of Neurology·A A SmitW Wieling
Mar 27, 2002·International Journal of Epidemiology·Diana R ElbourneAndy Vail
Sep 20, 2002·The New England Journal of Medicine·Elpidoforos S SoteriadesDaniel Levy
Dec 12, 2002·Journal of the American College of Cardiology·Michele BrignoleGino Lolli
May 8, 2003·JAMA : the Journal of the American Medical Association·Stuart J ConnollyUNKNOWN VPS II Investigators
Jun 3, 2004·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Francesco CrociGino Lolli
Jun 19, 2004·BMJ : British Medical Journal·David AtkinsUNKNOWN GRADE Working Group
Oct 14, 2004·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Wouter WielingRoy Freeman
Nov 3, 2004·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Michele BrignoleUNKNOWN Task Force on Syncope, European Society of Cardiology
Feb 3, 2005·Current Hypertension Reports·Jens Jordan
Aug 13, 2005·Journal of Neurology·Marcin TutajMax J Hilz
Aug 30, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Kye Hun KimJung Chaee Kang
Jun 13, 2006·Journal of Cardiovascular Electrophysiology·Nynke van DijkMark Linzer
Oct 19, 2006·Journal of the American College of Cardiology·Nynke van DijkUNKNOWN PC-Trial Investigators
Aug 19, 2007·The American Journal of Cardiology·Nynke van DijkMark Linzer
Aug 7, 2008·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·C T Paul KredietWouter Wieling
Jul 22, 2009·PLoS Medicine·David MoherUNKNOWN PRISMA Group
Aug 29, 2009·European Heart Journal·UNKNOWN Task Force for the Diagnosis and Management of SyncopeWouter Wieling
Dec 23, 2009·International Journal of Epidemiology·Margaret R StedmanM Alan Brookhart
Jan 6, 2010·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Jacobus J C M RommeNynke van Dijk
Oct 20, 2011·BMJ : British Medical Journal·Julian P T HigginsUNKNOWN Cochrane Statistical Methods Group
Mar 12, 2013·Progress in Cardiovascular Diseases·Satish R Raj, Samuel T Coffin
Apr 2, 2014·International Journal of Evidence-based Healthcare·Emmy De BuckPhilippe Vandekerckhove
Apr 5, 2014·Journal of Internal Medicine·W WielingJ R Halliwill
Jun 8, 2014·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Marco TomainoUNKNOWN International Study on Syncope of Uncertain Etiology 3 (ISSUE-3) Investigators
May 20, 2015·Statistics in Medicine·Michal KicinskiEvangelos Kontopantelis
Mar 22, 2018·European Heart Journal·Michele BrignoleUNKNOWN ESC Scientific Document Group

❮ Previous
Next ❯

Software Mentioned

Review Manager
Embase
MEDLINE
GRADE
Cochrane

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.