Physical Performance Testing in Kidney Transplant Candidates at the Top of the Waitlist.

American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation
Xingxing S ChengJane C Tan

Abstract

Frailty and poor physical function are associated with adverse kidney transplant outcomes, but how to incorporate this knowledge into clinical practice is uncertain. We studied the association between measured physical performance and clinical outcomes among patients on kidney transplant waitlists. Prospective observational cohort study. We studied consecutive patients evaluated in our Transplant Readiness Assessment Clinic, a top-of-the-waitlist management program, from May 2017 through December 2018 (N=305). We incorporated physical performance testing, including the 6-minute walk test (6MWT) and the sit-to-stand (STS) test, into routine clinical assessments. 6MWT and STS test results. The primary outcome was time to adverse waitlist outcomes (removal from waitlist or death); secondary outcomes were time to transplantation and time to death. We used linear regression to examine the relationship between clinical characteristics and physical performance test results. We used subdistribution hazards models to examine the association between physical performance test results and outcomes. Median 6MWT and STS results were 393 (IQR, 305-455) m and 17 (IQR, 12-21) repetitions, respectively. Clinical characteristics and Estimated Pos...Continue Reading

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Citations

Nov 29, 2020·Clinical Transplantation·Daniel J WatfordJane C Tan
Jun 15, 2021·Transplantation Direct·Margaret R StedmanJane C Tan

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