Physical Properties, Antimicrobial Activity and In Vivo Tissue Response to Apexit Plus

Materials
Roberto Alameda HoshinoPaulo Sérgio Cerri

Abstract

We investigated the physical properties, antimicrobial activity, and tissue reaction to Apexit Plus in comparison to Sealapex. Flow, radiopacity, setting time, and solubility were evaluated in each material. The antimicrobial activity against Enterococcus faecalis was performed. Polyethylene tubes containing Apexit Plus or Sealapex, and without material (control group) were implanted into the subcutaneous tissue of rats. At 7, 15, 30, and 60 days of implantation, the specimens were paraffin-embedded and the number of inflammatory cells (ICs) and the amount of birefringent collagen (BC) were quantified. The von Kossa reaction followed by immunohistochemistry for detection of alkaline phosphatase (ALP) was also performed. Statistical analysis was performed with ANOVA and Tukey test (p ≤ 0.05). The flow value of Apexit Plus was greater than Sealapex, whereas the radiopacity (3.44 mm Al) was lower than Sealapex (6.82 mm Al). Apexit Plus showed lower solubility and shorter initial and final setting (p 0.0001), whereas the antimicrobial activity was significantly greater than Sealapex. Although the number of ICs was higher in Apexit Plus (p = 0.0009) at 7 days, no significant difference was detected between Apexit Plus and Sealapex a...Continue Reading

References

Nov 1, 1988·Journal of Endodontics·R Caicedo, J A von Fraunhofer
Oct 27, 1997·The Journal of Investigative Dermatology·R L GalloM Bernfield
Apr 20, 2001·International Endodontic Journal·C D LaghiosC W Cutler
Sep 25, 2001·Dental Materials : Official Publication of the Academy of Dental Materials·D ØrstavikJ E Tibballs
Sep 27, 2003·International Endodontic Journal·E Schäfer, T Zandbiglari
May 24, 2008·Journal of Endodontics·Iris Slutzky-GoldbergShlomo Matalon
Jun 17, 2008·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·João Eduardo Gomes-FilhoAlessandra Cristina Gomes
May 5, 2009·Journal of Endodontics·Marco Antonio Húngaro DuarteIvaldo Gomes de Moraes
Apr 5, 2011·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Juliane M Guerreiro-TanomaruMário Tanomaru-Filho
Jul 24, 2012·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Naiana Viana ViolaPaulo Sérgio Cerri
Oct 4, 2012·Journal of Applied Oral Science : Revista FOB·Gabriela Alexandra Marín-BauzaCarlos Eduardo Saraiva Miranda
Apr 6, 2013·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Maria Giovanna GandolfiCarlo Prati
Feb 7, 2014·Dental Materials Journal·Ryan Jin Young Kim, Joo Hee Shin
Dec 18, 2014·Brazilian Dental Journal·Piedad S CañadasRoberto S Silva
Aug 4, 2015·Acta Informatica Medica : AIM : Journal of the Society for Medical Informatics of Bosnia & Herzegovina : časopis Društva Za Medicinsku Informatiku BiH·Alma Konjhodzic-PrcicAmra Vukovic
Mar 18, 2016·Brazilian Oral Research·Gabriely Cristinni RezendeElói Dezan
May 18, 2016·Journal of Clinical and Diagnostic Research : JCDR·Amulya VanapatlaRamkiran Dandolu
Jun 16, 2016·Brazilian Oral Research·Carlos Roberto Emerenciano BuenoEloi Dezan-Junior
Dec 17, 2016·Brazilian Dental Journal·Fernando Vazquez-GarciaJuliane Maria Guerreiro-Tanomaru
Jun 24, 2017·Journal of Clinical and Experimental Dentistry·Claudio PoggioGiampiero Pietrocola
Aug 3, 2017·Journal of Clinical and Diagnostic Research : JCDR·Srinidhi V BallullayaSagarika Balla
Aug 10, 2017·Advances in Clinical and Experimental Medicine : Official Organ Wroclaw Medical University·Małgorzata PawińskaJarosław Sidun
Jul 3, 2018·European Journal of Oral Sciences·Francine BenettiLuciano T A Cintra
Dec 6, 2018·Brazilian Dental Journal·Aline Teixeira MendesMarcus Vinícius Reis Só
Feb 1, 2019·International Endodontic Journal·C L Zordan-BronzelJ M Guerreiro-Tanomaru

❮ Previous
Next ❯

Citations

Mar 9, 2021·Restorative Dentistry & Endodontics·Roberto Alameda HoshinoPaulo Sérgio Cerri

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray

Software Mentioned

Sealapex
Apexit Plus
ImageJ
GraphPad Prism
Apexit
Image Pro - Express
GraphPad
ImageTool

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Applied Oral Science : Revista FOB
Heloisa Helena Pinho VelosoFlares Baratto Filho
International Endodontic Journal
U SalzJ-F Roulet
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics
Ayce Unverdi EldenizTimur Esener
© 2021 Meta ULC. All rights reserved