PMID: 591176Oct 1, 1977

Physical properties of Tamm-Horsfall glycoprotein and its glycopolypeptide

International Journal of Peptide and Protein Research
L M Hamlin, W W Fish


The molecular weight of the constituent glycopolypeptide chain of T-H glycoprotein was determined by sedimentation equilibrium under two entirely different sets of denaturing conditions. For both sets of denaturing conditions, the average molecular weight estimated for T-H glycopolypeptide was 74,000. The gel chromatographic behavior in 6M guanidium chloride of T-H glycopolypeptide with disulfide bonds intact as compared with its gel chromatographic behavior with disulfide bonds broken indicated that the glycopolypeptide is highly constrained by intrachain disulfide bonds.


Oct 1, 1968·The Biochemical Journal·R Pitt-Rivers, F S Impiombato
Nov 28, 1972·Biochimica Et Biophysica Acta·A J CleaveA R Peacocke
May 21, 1974·Biochemistry·C TanfordS Makino
Jul 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·J A Reynolds, C Tanford
Mar 1, 1970·The Biochemical Journal·F K Stevenson, P W Kent
Nov 1, 1970·The Biochemical Journal·A P FletcherW A Ratcliffe
Nov 1, 1970·The Biochemical Journal·A P FletcherW A Ratcliffe
Apr 27, 1971·Biochimica Et Biophysica Acta·J A FinniganJ C Marsden
Dec 28, 1966·Biochimica Et Biophysica Acta·T Friedmann, P Johnson
Sep 1, 1956·The Journal of Urology·W H BOYCE, F K GARVEY
Jun 1, 1959·Archives of Biochemistry and Biophysics·J S KING, W H BOYCE

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