Abstract
To explore antipsychotic (AP) medications and physical restraint use and their effects on physical function and cognition in older nursing home residents. This retrospective cohort studied involved 532 residents with dementia from 57 nursing homes participating in the Services and Health for Elderly in Long-Term Care study. Poisson log regression models explored the effect of physical restraint and/or AP medication use on cognitive or functional decline at 6 months. Physical restraint use was associated with a higher risk of both functional and cognitive decline compared with AP medication use alone. These risks were highest among residents receiving both AP medications and physical restraints, suggesting additive effects. Physical restraint use, and even more strongly, concurrent physical restraint and AP medication use, is related to function and cognitive decline in nursing home residents with dementia. Antipsychotic use is cautioned, but these results suggest physical restraint use is potentially more risky.
References
Oct 1, 1986·Journal of the American Geriatrics Society·J Cohen-Mansfield, N Billig
Jul 1, 1994·Journal of Gerontology·J N MorrisL A Lipsitz
Jun 1, 1996·Journal of the American Geriatrics Society·E CapezutiG Maislin
Aug 1, 1997·Journal of the American Geriatrics Society·C HawesM Nennstiel
Jan 5, 2000·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·J N MorrisS A Morris
May 3, 2000·Age and Ageing·A B BurrowsC Phillips
Oct 9, 2004·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Oscar J de VriesUNKNOWN European Academy of Medicine of Ageing-Course III
Nov 24, 2006·Medical Care·Laura PekkarinenAnja Noro
Jan 1, 2009·BMC Health Services Research·John P HirdesReudi Gilgen
Mar 6, 2009·Geriatrics & Gerontology International·Manuel Eskildsen, Thomas Price
Mar 13, 2009·International Journal of Geriatric Psychiatry·Zhanlian FengVincent Mor
May 1, 2009·BMC Health Services Research·Leonard C GrayJohn N Morris
Jan 23, 2010·Journal of Aging & Social Policy·Kathryn HyerChristopher E Johnson
Feb 15, 2011·Journal of the American Geriatrics Society·Petra KoczyDoris Bredthauer
Jan 11, 2012·BMC Health Services Research·Graziano OnderUNKNOWN SHELTER project
Jul 20, 2013·Journal of Nursing Management·Carol A WongLisa Ducharme
Nov 2, 2013·BMC Health Services Research·Andrea D FoebelUNKNOWN ideas PNC research team
Feb 18, 2014·Journal of the American Medical Directors Association·Ramona BackhausJan P H Hamers
Sep 30, 2014·Journal of the American Medical Directors Association·Andrea D FoebelUNKNOWN SHELTER Study Investigators
Citations
Mar 10, 2016·Journal of the American Medical Directors Association·Patricia Abele, John E Morley
Oct 27, 2016·Journal of the American Medical Directors Association·Davide L VetranoUNKNOWN Italian Group for Appropriate Drug Prescription in the Elderly (I-GrADE)
Nov 5, 2016·Drugs & Aging·Maryse Lapeyre-Mestre
Nov 11, 2016·Drugs & Aging·Kathryn J StockColleen J Maxwell
Dec 3, 2016·International Journal of Geriatric Psychiatry·Marja KuronenHannu Koponen
May 8, 2018·Health Services Research·Nina R JoyceDavid C Grabowski
Feb 17, 2017·Therapeutic Advances in Drug Safety·Carole Parsons
Jan 5, 2019·International Journal of Older People Nursing·Emma N BellengerLyndal Bugeja
Feb 23, 2018·Dementia·Rainbow Th HoJanet Kl Kwok
Jul 2, 2020·International Psychogeriatrics·Liat AyalonElitzur Bar Asher-Sigal
Sep 6, 2020·Journal of Clinical Nursing·Lihui Pu, Wendy Moyle
Mar 19, 2020·Frontiers in Psychiatry·Wendy de BruijnRoel J T Mocking
Jul 23, 2020·Revista brasileira de enfermagem·Romulo DelvallePatrícia de Fátima Augusto Barros
Jul 13, 2017·Behavioral Sciences·Christopher JohnsonRoxanna Johnson
Aug 14, 2019·International Journal of Environmental Research and Public Health·Qilin ZhangErpeng Liu
Dec 4, 2020·Journal of Advanced Nursing·Jens AbrahamRalph Möhler
Apr 4, 2021·International Journal of Environmental Research and Public Health·Lauren M RobinsTerry P Haines
Apr 7, 2021·Salud colectiva·Luis Nocete NavarroAlberto Fernández Liria
Jun 8, 2021·International Journal of Geriatric Psychiatry·Lídia SousaLia Fernandes
Jun 5, 2020·Journal of the American Medical Directors Association·John P HirdesKaye Phillips
Sep 24, 2021·Perspectives in Psychiatric Care·Pi-Chueh TsaiI-Shiang Tzeng
Jul 7, 2021·Nursing Forum·Amal Al GhassaniAbdallah Abu Khait