Physicians' approaches to the use of gastroprotective strategies in low-risk non-steroidal anti-inflammatory drug users

Alimentary Pharmacology & Therapeutics
S K MurthyLaura E Targownik

Abstract

Many doctors unnecessarily prescribe gastroprotective strategies to non-steroidal anti-inflammatory drugs users at low risk of non-steroidal anti-inflammatory drug-related gastrointestinal complications. To identify factors that predict the overuse of gastroprotective strategies in low-risk non-steroidal anti-inflammatory drug users. We distributed a questionnaire to family doctors and general internists consisting of a clinical vignette describing a low-risk hypothetical patient with osteoarthritis who was a candidate for non-steroidal anti-inflammatory drug therapy. Respondents were asked whether they would prescribe this patient a gastroprotective strategy and to estimate the annual risk of that patient developing a gastrointestinal complication with non-steroidal anti-inflammatory drug use. Respondents inappropriately recommending a gastroprotective strategy were compared with respondents who opted not to use gastroprotection. We received 340 responses (response rate of 28.3%), of which 278 supplied analysable data. Thirty-five percent of respondents inappropriately recommended a gastroprotective strategy for the low-risk subject. Inappropriate prescribers were significantly more likely to overestimate the risk of gastroint...Continue Reading

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Citations

Dec 4, 2009·American Journal of Therapeutics·Gregory A CotéColin W Howden
Nov 14, 2008·Alimentary Pharmacology & Therapeutics·E P M van VlietP D Siersema
Aug 9, 2007·Journal of Evaluation in Clinical Practice·Mieke L van DrielThierry Christiaens
Mar 13, 2010·Alimentary Pharmacology & Therapeutics·V E ValkhoffE J Kuipers
Mar 24, 2016·International Journal of Clinical Pharmacy·Sabrina MontagnaniCorrado Blandizzi
Aug 6, 2008·European Journal of Gastroenterology & Hepatology·Evelyn P M van VlietPeter D Siersema
Jul 18, 2009·Journal of Clinical Gastroenterology·Glen A DohertyFrank E Murray

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