Physico- and bio-activities of nanoscale regenerated cellulose nonwoven immobilized with lysozyme

Materials Science & Engineering. C, Materials for Biological Applications
Yue LiuJonathan Y Chen

Abstract

Lysozyme-cellulose conjugates are of wide interest for food packaging, tissue scaffolding, wound healing, and antimicrobial applications. Here a recycled cotton-based source of regenerated cellulose in combination with carboxylated carbon nanotubes and graphene oxide was configured as nonwoven nanofibrous mats through electrospinning and utilized to immobilize lysozyme. Scanning electron microscopy, Fourier transform-infrared spectra, thermal-gravimetric analysis, tensile test, and antibacterial assessments were conducted to characterize and determine physical and bioactive properties of the nonwoven nanofibrous mats. The resulted cellulose-lysozyme conjugates were found to have robust bioactivity with no indication of cell cytotoxicity. The study confirmed that the carbon-nanoparticle-modified cellulose nonwoven mats revealed a high antimicrobial activity after immobilization of lysozyme.

Citations

Mar 7, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Raquel BecerrilFilomena Silva
Dec 31, 2020·Pharmaceutics·Alma Akhmetova, Andrea Heinz
Mar 17, 2021·Critical Reviews in Food Science and Nutrition·Dur E SameenYaowen Liu
Mar 30, 2021·Biosensors & Bioelectronics·Madalina Elena CulicaSergiu Coseri

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