Physicochemical characteristics of OxyVita hemoglobin, a zero-linked polymer: liquid and powder preparations

Artificial Cells, Blood Substitutes, and Immobilization Biotechnology
John P HarringtonHanna Wollocko

Abstract

OxyVita-zero-link polymerized hemoglobin (OxyVita Hb) is a novel generation hemoglobin based oxygen carrier (HBOC). Our focus in this paper is to address the question of "Why is OxyVita Hemoglobin different than the previous generation of HBOCs?" Several critical related topics will be discussed: 1) OxyVita's unique chemistry; 2) the introduction of a viable powder form of OxyVita hemoglobin for dissolution in IV water or other IV fluids; 3) the physiochemical characteristics of OxyVita hemoglobin preparations; 4) the ability to formulate different products based upon specific applications; and 5) the important storage properties essential for use in a wide range of geographical locations.

References

Jan 1, 1994·Physiological Reviews·B Rippe, B Haraldsson
Jun 1, 1995·Molecular Medicine Today·A I Alayash, R E Cashon
Mar 3, 2004·Free Radical Biology & Medicine·John S OlsonDouglas D Lemon
Sep 13, 2005·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·Seetharama A AcharyaPaul K Smith
Mar 17, 2007·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·John P HarringtonRhoda Elison Hirsch
May 5, 2007·Expert Opinion on Biological Therapy·Abdu I AlayashPaul W Buehler
Jan 26, 2008·Journal of the Medical Library Association : JMLA·Frances H Lynch, Judith L Rieke
Jun 17, 2008·Biochimica Et Biophysica Acta·Robert M Winslow
Mar 4, 2010·Artificial Cells, Blood Substitutes, and Immobilization Biotechnology·John P HarringtonHanna Wollocko

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Citations

Dec 4, 2010·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·John P Harrington, Hanna Wollocko
Mar 5, 2016·Artificial Cells, Nanomedicine, and Biotechnology·Francoise ArnaudPaula F Moon-Massat
Dec 13, 2016·Artificial Cells, Nanomedicine, and Biotechnology·Hanna WollockoJohn P Harrington
Mar 25, 2017·Journal of Functional Biomaterials·Kazuaki TaguchiMasaki Otagiri
Jan 1, 2011·Journal of Functional Biomaterials·John P Harrington, Hanna Wollocko
Dec 12, 2017·Biotechnology Progress·Athul RajeshJacob Elmer
Jan 10, 2018·Bioengineering & Translational Medicine·Devon ZimmermanJacob J Elmer

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