Physicochemical characterization of ambient PM2.5 in Tehran air and its potential cytotoxicity in human lung epithelial cells (A549)

The Science of the Total Environment
Anoushiravan MohseniBandpiAbdolazim Alinejad

Abstract

As air pollution is a major problem in Tehran, this study aimed to investigate the physicochemical characterization of the water-soluble and organic contents of ambient PM2.5 in Tehran and determine its in vitro toxicological impact on human lung epithelial cells (A549). A total of 11 sampling stations were selected, including three categories: traffic, urban, and suburban. All sampling was carried out in the spring and summer of 2015. Ion chromatography (IC), inductively coupled plasma atomic emission spectroscopy (ICP-AES), and GC-MS were used to analyze ionic compounds, heavy metals, and polycyclic aromatic hydrocarbons (PAHs), respectively, and an ELISA reader was used for cytotoxicity analysis. The most prevalent ionic species found for all three categories was SO42-. PAH concentrations were 43.45±32.71, 50.51±37.27, and 29.13±33.29ng/m3 for traffic, urban, and suburban stations, respectively. For all sampling stations, Al and Fe had the highest values among the investigated heavy metals. Cell viability measurements, carried out using the MTT assay, showed that all three categories of samples cause cytotoxicity, although the urban station samples showed higher cytotoxicity than those from the other stations (p˂0.05). Based...Continue Reading

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Citations

Mar 12, 2018·Environmental Science and Pollution Research International·Maryam YarahmadiAbbas Shahsavani
Jan 10, 2018·Archives of Environmental Contamination and Toxicology·Khosro AshrafiAbbas Shahsavani
Aug 19, 2020·Environmental Science and Pollution Research International·Lili XinZengli Zhang
Oct 3, 2018·Environmental Science and Pollution Research International·Xiaoning LeiJiahui Chen
Jul 25, 2018·Environmental Science and Pollution Research International·Mostafa HadeiAbbas Shahsavani
Jul 13, 2019·Journal of Environmental Health Science & Engineering·Maryam FarajiAlireza Mesdaghinia
Dec 15, 2019·International Journal of Environmental Research and Public Health·Tuan Hung NgoKai Hsien Chi
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Dec 16, 2018·Environmental Geochemistry and Health·Saeed Motesaddi ZarandiYadolah Fakhri
Jun 27, 2020·Reviews on Environmental Health·Huibin GuoSijing Huang
Jun 22, 2021·Journal of Environmental Health Science & Engineering·Javad TorkashvandMajid Kermani
Aug 8, 2021·Environmental Science and Pollution Research International·Tahereh RahmatiniaFarzad Fanaei
Nov 12, 2019·Environmental Science & Technology·Antoine S AlmeidaRegina M B O Duarte

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