Physiologic-Based Cord Clamping Maintains Core Temperature vs. Immediate Cord Clamping in Near-Term Lambs

Frontiers in Pediatrics
Douglas A BlankGraeme R Polglase

Abstract

Background: Physiologic-based cord clamping (PBCC) involves deferring umbilical cord clamping until after lung aeration. It is unclear if infant is at risk of becoming hypothermic during PBCC. Objectives: To test if PBCC would maintain core temperature more effectively than immediate cord clamping (ICC). Design: At 0.93 gestation, fetal lambs were surgically exteriorized and instrumented from pregnant ewes under general anesthesia. Prior to the start of the experiment, lambs were thoroughly dried, placed on hot water bottles, and core temperature was continuously monitored using a rectal thermometer. PBCC lambs (n = 21), received intermittent positive pressure ventilation (iPPV) for ≥5 min prior to umbilical cord clamping. In ICC lambs (n = 23), iPPV commenced within 60 s after umbilical cord clamping. iPPV was provided with heated/humidified gas. Lambs were moved under a radiant warmer after umbilical cord clamping. Additional warmth was provided using a plastic overlay, hairdryer, and extra water bottles, as needed. Two-way mixed and repeated measures one-way ANOVAs were used to compare temperature changes between and within a single group, respectively, over time. Results: Basal fetal parameters including core temperature we...Continue Reading

References

Jan 1, 1972·Biology of the Neonate·A C Yao, J Lind
Sep 1, 1984·The Journal of Pediatrics·M Kaplan, A I Eidelman
Jan 1, 1994·Experimental Physiology·P Andrianakis, D Walker
Jan 18, 2002·Journal of Applied Physiology·Helen P LaburnDuncan Mitchell
Jan 7, 2006·Pediatrics·Narendra AladangadyBarbara M Holland
Feb 14, 2007·Pediatrics·Abbot R LaptookUNKNOWN Neonatal Research Network
Jul 7, 2010·Archives of Pediatrics & Adolescent Medicine·Luke C MullanyJames M Tielsch
Feb 2, 2011·The Journal of Pediatrics·Marianne Thoresen
Jul 25, 2012·Obstetrics and Gynecology·Joseph W KaempfGary Grunkemeier
Aug 4, 2012·Journal of Perinatology : Official Journal of the California Perinatal Association·Y-S JiaJ Lin
Sep 8, 2012·Clinics in Perinatology·Satyan Lakshminrusimha
Jun 19, 2013·Pediatrics·Lisa K McCarthyColm P F O'Donnell
Apr 26, 2016·Journal of Perinatology : Official Journal of the California Perinatal Association·H K OatleyJ E Lawn
May 18, 2016·The Journal of Pediatrics·Emilija WilsonUNKNOWN Effective Perinatal Intensive Care in Europe (EPICE) Research Group
Jun 16, 2016·American Journal of Perinatology·Jameel WinterKaren Fairchild
Jul 19, 2016·Paediatrics & Child Health·Michael SgroNeil Gandhi
Oct 30, 2016·The Journal of Pediatrics·Anup KatheriaNeil Finer
Oct 31, 2017·The New England Journal of Medicine·William Tarnow-MordiUNKNOWN Australian Placental Transfusion Study Collaborative Group
Nov 4, 2017·American Journal of Obstetrics and Gynecology·Michael FogartyWilliam Tarnow-Mordi
Nov 7, 2017·The Journal of Pediatrics·Lorraine McGroryC Omar F Kamlin
Dec 2, 2017·Archives of Disease in Childhood. Fetal and Neonatal Edition·Graeme R PolglaseStuart B Hooper
Dec 7, 2017·Archives of Disease in Childhood. Fetal and Neonatal Edition·Douglas A BlankStuart B Hooper
Dec 17, 2017·The Journal of Pediatrics·Abbot R LaptookUNKNOWN Generic and Moderate Preterm Subcommittees of the NICHD Neonatal Research Network
Jul 24, 2018·Resuscitation·Douglas A BlankPeter G Davis
Oct 5, 2018·Archives of Disease in Childhood. Fetal and Neonatal Edition·Emma BrouwerArjan B Te Pas
Feb 8, 2019·Archives of Disease in Childhood. Fetal and Neonatal Edition·Philip L J DeKoninckRyan J Hodges
Feb 8, 2019·Archives of Disease in Childhood. Fetal and Neonatal Edition·Aidan J KashyapRyan J Hodges
May 28, 2019·Archives of Disease in Childhood. Fetal and Neonatal Edition·Aidan J KashyapPhilip L J DeKoninck
Jun 14, 2019·Journal of Applied Physiology·Erin V McGillickKelly J Crossley
Aug 1, 2019·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A J KashyapR J Hodges
Aug 30, 2019·Archives of Disease in Childhood. Fetal and Neonatal Edition·Elizabeth E FogliaSarah J Ratcliffe

❮ Previous
Next ❯

Methods Mentioned

BETA
cesarean section
sedation

Software Mentioned

SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.