Physiologic pharmacokinetic modeling

Journal of Clinical Pharmacology
W A Colburn


Although physiologic modeling has not gained the widespread acceptance that was originally projected, it may serve as the basis for future PK/PD modeling approaches. In addition, with more effort applied to developing in vitro and animal-to-human predictions, physiologic modeling may assume a higher position in the pharmacokinetic modeling hierarchy.


Aug 1, 1979·Journal of Pharmacokinetics and Biopharmaceutics·W A Colburn
Jan 1, 1986·Comparative Biochemistry and Physiology. A, Comparative Physiology·R A Coulson
Mar 1, 1987·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·H W Ruelius
Jan 1, 1987·Biopharmaceutics & Drug Disposition·G SchuhmannH Kurz
Jun 1, 1987·Journal of Pharmacokinetics and Biopharmaceutics·J M GalloD G Perrier
Jan 1, 1986·Bulletin of Mathematical Biology·K B Bischoff
Jan 1, 1985·Pharmacology & Therapeutics·M Rowland
Jan 15, 1986·Biochemical Pharmacology·J V Watson, P Workman
Oct 1, 1973·Journal of Pharmacokinetics and Biopharmaceutics·R L Dedrick
Oct 1, 1983·Journal of Pharmaceutical Sciences·L E Gerlowski, R K Jain
Jan 1, 1980·Pharmacology & Therapeutics·R J LutzD S Zaharko
Jan 1, 1982·Journal of Pharmaceutical Sciences·J M Collins, R L Dedrick
Apr 1, 1982·Journal of Pharmacokinetics and Biopharmaceutics·H Boxenbaum
Apr 1, 1979·Journal of Pharmacokinetics and Biopharmaceutics·K J Himmelstein, R J Lutz

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May 6, 2011·Journal of Pharmaceutical Sciences·Joost WesterhoutElizabeth C M De Lange
Oct 1, 1988·Journal of Clinical Pharmacology
Apr 1, 1995·Journal of Pharmacokinetics and Biopharmaceutics·S B CharnickH Sato
Apr 1, 1993·Journal of Interferon Research·J A KerryB F Cheetham

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