PMID: 6172398Jan 1, 1981Paper

Physiological and anatomical characteristics of primary vestibular afferent neurons in the bullfrog

The International Journal of Neuroscience
V HonrubiaI R Schwartz

Abstract

Intracellular recordings were made in the VIIIth nerve of the bullfrog (Rana catesbiana) to measure the membrane characteristics and obtain records of spontaneous and evoked spike activity of primary semicircular canal afferents. Physiological stimulation of the canals was achieved by rotating the preparation on a servomotor driven turntable with the animals' head centered in the rotational axis. The responses of each neuron to sinusoidal rotations at frequencies of 0.05Hz, 0.5Hz and for impulsive accelerations of 400 deg/sec2 were obtained. Membrane characteristics measured included the cell resting and action potential amplitude, and spike-activation threshold for applied currents. Physiologically characterized neurons were injected with horseradish peroxidase by applying pneumatic pressure and/or iontophoretic currents to the micropipettes containing 5% HRP in 1 M KCI. Following survival times of 12--48 h, the VIIIth nerve and attached vestibular end organ was removed for histochemical processing using a diaminobenzidine procedure to visualize the HRP reaction product. Light microscopy was used to discern the anatomical features of the neurons and to trace their peripheral dendritic trajectories from the ganglion to their te...Continue Reading

Citations

Nov 26, 1990·Brain Research·S F Myers, E R Lewis
Dec 1, 1983·Journal of Neuroscience Methods·A A Perachio, M J Correia
May 1, 1994·Hearing Research·P S GuthC H Norris
Apr 23, 2005·Journal of Neurophysiology·Stephen M HighsteinRichard D Boyle
Apr 1, 1984·The Laryngoscope·V HonrubiaI R Schwartz
Mar 8, 1991·Brain Research·S F Myers, E R Lewis
Mar 22, 2006·The Anatomical Record. Part A, Discoveries in Molecular, Cellular, and Evolutionary Biology·Timothy E Hullar
Mar 11, 2003·Journal of Neurophysiology·Xiaohong SiJ David Dickman
Oct 6, 1997·Journal of Neurophysiology·H StrakaN Dieringer
Nov 7, 2019·Journal of Neurophysiology·Michael G Paulin, Larry F Hoffman
Nov 22, 1994·The Journal of Comparative Neurology·I Reichenberger, N Dieringer
Apr 8, 1994·The Journal of Comparative Neurology·R A Baird, N R Schuff
Jul 27, 2021·Frontiers in Neuroscience·Ingrid ReichenbergerHans Straka

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