Physiological aspects of cardiac tissue engineering

American Journal of Physiology. Heart and Circulatory Physiology
Thomas EschenhagenArne Hansen

Abstract

Cardiac tissue engineering aims at repairing the diseased heart and developing cardiac tissues for basic research and predictive toxicology applications. Since the first description of engineered heart tissue 15 years ago, major development steps were directed toward these three goals. Technical innovations led to improved three-dimensional cardiac tissue structure and near physiological contractile force development. Automation and standardization allow medium throughput screening. Larger constructs composed of many small engineered heart tissues or stacked cell sheet tissues were tested for cardiac repair and were associated with functional improvements in rats. Whether these approaches can be simply transferred to larger animals or the human patients remains to be tested. The availability of an unrestricted human cardiac myocyte cell source from human embryonic stem cells or human-induced pluripotent stem cells is a major breakthrough. This review summarizes current tissue engineering techniques with their strengths and limitations and possible future applications.

References

Oct 8, 1992·The American Journal of Cardiology·A M Katz
Jan 1, 1991·Journal of Biomechanics·H H VandenburghJ Shansky
Jul 1, 1997·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·T EschenhagenE L Elson
Jun 6, 1998·Cardiovascular Research·J WeilH Scholz
Jul 22, 1998·Circulation Research·P Anversa, J Kajstura
Jul 22, 1998·Circulation Research·M H Soonpaa, L J Field
Aug 26, 1998·Cardiovascular Research·J van der VeldenG J Stienen
Nov 6, 1998·Science·J A ThomsonJ M Jones
Mar 4, 2000·Biotechnology and Bioengineering·W H ZimmermannT Eschenhagen
Apr 1, 2000·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·C FinkT Eschenhagen
Dec 21, 2000·American Journal of Physiology. Heart and Circulatory Physiology·M PapadakiL E Freed
Apr 5, 2001·Nature·D OrlicP Anversa
May 10, 2001·Journal of Molecular and Cellular Cardiology·M ZhangC E Murry
Feb 9, 2002·Circulation Research·W-H ZimmermannT Eschenhagen
Feb 20, 2002·Journal of Molecular and Cellular Cardiology·Hans ReineckeCharles E Murry
Sep 18, 2002·Journal of Molecular and Cellular Cardiology·Jaime DeSantiagoDonald M Bers
Dec 14, 2002·Basic Research in Cardiology·Thomas EschenhagenWolfram-Hubertus Zimmermann
Oct 11, 2003·American Journal of Physiology. Heart and Circulatory Physiology·Milica RadisicGordana Vunjak-Novakovic
Nov 13, 2004·American Journal of Physiology. Heart and Circulatory Physiology·Milica RadisicGordana Vunjak-Novakovic
Dec 3, 2004·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Keith BaarRobert G Dennis
Dec 18, 2004·Proceedings of the National Academy of Sciences of the United States of America·Milica RadisicGordana Vunjak-Novakovic
Apr 27, 2005·Circulation·Michael HofmannHelmut Drexler
Jul 9, 2005·Circulation Research·Michael E DavisRichard T Lee
Oct 15, 2005·In Vitro Cellular & Developmental Biology. Animal·Hyoungshin ParkGordana Vunjak-Novakovic
Jan 28, 2006·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Tatsuya ShimizuTeruo Okano
Mar 18, 2006·Circulation Research·Thomas EschenhagenAndré G Kléber
Apr 4, 2006·Nature Medicine·Wolfram-Hubertus ZimmermannThomas Eschenhagen
Apr 4, 2006·Nature Medicine·Yoshinori MiyaharaHidezo Mori
May 3, 2006·Circulation·Xi-Min GuoXiangzhong Jerry Yang
Jun 20, 2006·Biophysical Journal·Clara F AsnesTetsuro Wakatsuki
Jul 6, 2006·Circulation·Hiroshi NaitoWolfram-Hubertus Zimmermann
Jan 4, 2007·Circulation·Andrew N MorrittWayne A Morrison

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Citations

Feb 22, 2013·Stem Cell Research & Therapy·Nimalan ThavandiranMilica Radisic
Nov 28, 2013·Pharmacology & Therapeutics·Simon R FosterWalter G Thomas
Oct 25, 2013·British Medical Bulletin·Suzanne M WattJaap Jan Zwaginga
Dec 3, 2014·The International Journal of Biochemistry & Cell Biology·Rodney J Dilley, Wayne A Morrison
Oct 10, 2013·Stem Cells Translational Medicine·Amanda J LeblancStuart K Williams
Jun 1, 2015·Advanced Drug Delivery Reviews·Alexandra EderThomas Eschenhagen
May 10, 2015·Advanced Drug Delivery Reviews·Nicole T Feric, Milica Radisic
Apr 30, 2014·Revista Española De Cardiología·Carolina Gálvez-MontónAntoni Bayes-Genis
Oct 17, 2014·Thrombosis and Haemostasis·C PatraF B Engel
Nov 26, 2015·Biochimica Et Biophysica Acta·Kaja BreckwoldtThomas Eschenhagen
May 3, 2015·Biomaterials·Adriana BlazeskiLeslie Tung
May 20, 2015·Biomaterials·Amandine F G Godier-FurnémontWolfram-Hubertus Zimmermann
May 24, 2014·Journal of Molecular and Cellular Cardiology·Marc N HirtThomas Eschenhagen
Apr 30, 2016·Advanced Drug Delivery Reviews·Marco SantoroAntonios G Mikos
May 24, 2016·Stem Cell Reports·Ingra MannhardtArne Hansen
Aug 31, 2016·Scientific Reports·Jonas SchwanStuart G Campbell
Jan 18, 2014·Circulation Research·Marc N HirtThomas Eschenhagen
Apr 30, 2017·Circulation Research·Florian WeinbergerThomas Eschenhagen
Oct 4, 2012·Expert Review of Cardiovascular Therapy·Mai T Lam, Joseph C Wu
Jul 10, 2013·Macromolecular Bioscience·Antonella SilvestriGianluca Ciardelli
Oct 26, 2013·Tissue Engineering. Part a·Ingra VollertThomas Eschenhagen
Nov 25, 2014·Advanced Functional Materials·Su Ryon ShinAli Khademhosseini
Dec 14, 2019·Advanced Materials·Limor Zwi-DantsisMolly M Stevens
Nov 1, 2013·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Irene C TurnbullKevin D Costa
May 7, 2020·Anesthesia and Analgesia·Detlef ObalVivianne L Tawfik
Mar 5, 2013·American Journal of Physiology. Heart and Circulatory Physiology·William C Stanley, Kara Hansell Keehan
Mar 28, 2017·Experimental Biology and Medicine·Sean P SheehyKevin K Parker
May 12, 2017·Nature Protocols·Kaja BreckwoldtArne Hansen
Aug 24, 2016·Biomaterials·Weitao JiaAli Khademhosseini
Mar 10, 2021·European Heart Journal·Massimiliano GnecchiPeter J Schwartz
Sep 2, 2020·Pharmacological Research : the Official Journal of the Italian Pharmacological Society·Lorenzo SantiniRaffaele Coppini
Jul 24, 2021·Essays in Biochemistry·Parvin AlizadehNureddin Ashammakhi

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