Physiological control of blood pumps using intrinsic pump parameters: a computer simulation study

Artificial Organs
Guruprasad A Giridharan, Mikhail Skliar

Abstract

Implantable flow and pressure sensors, used to control rotary blood pumps, are unreliable in the long term. It is, therefore, desirable to develop a physiological control system that depends only on readily available measurements of the intrinsic pump parameters, such as measurements of the pump current, voltage, and speed (in revolutions per minute). A previously proposed DeltaP control method of ventricular assist devices (VADs) requires the implantation of two pressure sensors to measure the pressure difference between the left ventricle and aorta. In this article, we propose a model-based method for estimating DeltaP, which eliminates the need for implantable pressure sensors. The developed estimator consists of the extended Kalman filter in conjunction with the Golay-Savitzky filter. The performance of the combined estimator-VAD controller system was evaluated in computer simulations for a broad range of physical activities and varying cardiac conditions. The results show that there was no appreciable performance degradation of the estimator-controller system compared to the case when DeltaP is measured directly. The proposed approach effectively utilizes a VAD as both a pump and a differential pressure sensor, thus elimin...Continue Reading

References

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Oct 31, 2002·Artificial Organs·Guruprasad A Giridharan, Mikhail Skliar
Jun 26, 2003·Artificial Organs·Guruprasad A Giridharan, Mikhail Skliar
Oct 23, 2004·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Guruprasad A GiridharanMikhail Skliar

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Citations

Jul 9, 2011·Annals of Biomedical Engineering·Shaun D GregoryJohn F Fraser
Jun 26, 2003·Artificial Organs·Guruprasad A Giridharan, Mikhail Skliar
Feb 15, 2007·Artificial Organs·Seongjin ChoiJames F Antaki
Mar 9, 2007·Artificial Organs·Paul S Malchesky
Jul 17, 2010·Artificial Organs·Nicholas Richard GaddumMark John Pearcy
May 21, 2010·Artificial Organs·Nicholas Richard GaddumMark John Pearcy
Aug 14, 2012·Artificial Organs·Shaun David GregoryDaniel Timms
Aug 14, 2012·Artificial Organs·Guruprasad A GiridharanMark S Slaughter
Oct 8, 2009·Biomedizinische Technik. Biomedical Engineering·Rüdger KoppRolf Rossaint
Nov 2, 2013·The Journal of Thoracic and Cardiovascular Surgery·Siavash S Asgari, Pramod Bonde
Jan 1, 2014·Artificial Organs·Nicholas R GaddumRobert Salamonsen
Nov 19, 2015·Australasian Physical & Engineering Sciences in Medicine·Selim Bozkurt
Mar 13, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Feng HuangXin Fu
Jul 29, 2018·Annals of Biomedical Engineering·Anastasios PetrouMarianne Schmid Daners
Sep 25, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yu WangGuruprasad A Giridharan
Jan 20, 2011·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yu Chang, Bin Gao
Jan 24, 2007·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Guruprasad A GiridharanGeorge M Pantalos
Jun 10, 2009·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yi Wu
Dec 18, 2012·Physiological Measurement·Abdul-Hakeem H AlOmariNigel H Lovell
Feb 28, 2014·Methods of Information in Medicine·E C KarvounisD I Fotiadis
Sep 24, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Yu WangGuruprasad A Giridharan
Nov 15, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Y WangG A Giridharan
May 7, 2013·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Mickey S IsingGuruprasad A Giridharan
Jul 4, 2013·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Kevin G SoucyGuruprasad A Giridharan
May 2, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Vakhtang TchantchaleishviliH Todd Massey
Sep 10, 2015·The International Journal of Artificial Organs·Kim A M A PenningsMarcel C M Rutten
Jul 22, 2019·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Daisuke OgawaEisuke Tatsumi
May 29, 2012·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Guruprasad A GiridharanSteven C Koenig
Aug 18, 2021·The International Journal of Artificial Organs·Martin ElenkovMargit Gföhler

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