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Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

The Journal of Experimental Medicine

Feb 1, 1996

Frederic J De SauvageMarilyn Moore

PMID: 8627177

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Abstract

Thrombopoietin (TPO) has recently been cloned and shown to regulate megakaryocyte and platelet production by activating the cytokine receptor c-mpl. To determine whether TPO is the only ligand for c-mpl and the major regulator of megakaryocytopoiesis, TPO deficient mice were generated b...read more

Mentioned in this Paper

Thrombopoietin Measurement
Megakaryocytes
Gene Dosage
Investigation of Megakaryocytes
Ligands
Mutagenesis Process
Northern Blot
Interleukin-3
Ploidies
Complete Blood Count
56
Paper Details
References
    • References11
    • Citations184
    • References11
    • Citations184
  • Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

    The Journal of Experimental Medicine

    Feb 1, 1996

    Frederic J De SauvageMarilyn Moore

    PMID: 8627177

    DOI:

    Abstract

    Thrombopoietin (TPO) has recently been cloned and shown to regulate megakaryocyte and platelet production by activating the cytokine receptor c-mpl. To determine whether TPO is the only ligand for c-mpl and the major regulator of megakaryocytopoiesis, TPO deficient mice were generated b...read more

    Mentioned in this Paper

    Thrombopoietin Measurement
    Megakaryocytes
    Gene Dosage
    Investigation of Megakaryocytes
    Ligands
    56

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    Paper Details
    References
    • References11
    • Citations184
    • References11
    • Citations184
  • Get paper from

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