Physiological responses during downhill walking: A new exercise modality for subjects with chronic obstructive pulmonary disease?

Chronic Respiratory Disease
Carlos Augusto CamilloThierry Troosters

Abstract

Skeletal muscle quadriceps low-frequency fatigue (LFF) during exercise promotes improvements in exercise capacity with exercise training. In healthy subjects, eccentric muscle work induced by downhill walking (DW) generates higher muscular stress, whilst metabolic cost is lower compared to level walking (LW). We investigated quadriceps LFF and metabolic cost of DW in patients with chronic obstructive pulmonary disease. Ten participants (67 ± 7 years, FEV1 51 ± 15% predicted) performed DW, DW carrying a load (DWL) of 10% body weight via vest and LW, in random order. Quadriceps potentiated twitch force (TWqpot) was assessed before and after each walk, and muscle damage was assessed before and 24 hours after each walk via serum creatine kinase (CK) levels. Ventilation (VE) and oxygen consumption (VO2) were measured via breath-by-breath analysis during each walk. DW and DWL resulted in a greater decrease in TWqpot (-30 ± 14 N in DW, p < 0.05; and -22 ± 16 N in DWL, p < 0.05) compared to LW (-3 ± 21 N, p > 0.05). CK levels only increased 24 hours following DW and DWL (p < 0.05). DW and DWL showed lower VE and VO2 than LW (p < 0.05). DW is associated with enhanced quadriceps LFF and lower cardiorespiratory costs than LW. The addition...Continue Reading

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Citations

Dec 31, 2015·Asian Journal of Sports Medicine·Azadeh ErfaniSeyed Ali Javad Mousavi
Apr 8, 2017·Expert Review of Respiratory Medicine·Gianna W BiscaChristian R Osadnik
Apr 23, 2016·The European Respiratory Journal·Leandro Cruz MantoaniRoberto A Rabinovich
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May 24, 2020·The European Respiratory Journal·Carlos Augusto CamilloThierry Troosters
Jul 26, 2019·Physiotherapy Theory and Practice·Aqsa MujaddadiDeepak Talwar
Sep 17, 2019·Journal of Applied Physiology·Giuseppe CoratellaPierre Clos
Jan 30, 2020·Frontiers in Physiology·Mathieu MarillierJ Alberto Neder
Aug 5, 2017·Chronic Respiratory Disease·Fernanda Machado RodriguesChristian Osadnik
Aug 5, 2017·Chronic Respiratory Disease·Rafael MesquitaMartijn A Spruit
Feb 11, 2021·Chest·Joana Cruz, Chris Burtin

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BETA
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Statistical Analysis SAS

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