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Physiology and immunology of the cholinergic antiinflammatory pathway

The Journal of Clinical Investigation

Feb 3, 2007

Kevin J Tracey

Abstract

Cytokine production by the immune system contributes importantly to both health and disease. The nervous system, via an inflammatory reflex of the vagus nerve, can inhibit cytokine release and thereby prevent tissue injury and death. The efferent neural signaling pathway is termed the c...read more

Mentioned in this Paper

Septicemia
Cholinergic Fibers
Ischemia
Biochemical Pathway
Immune System
Endotoxemia
Cholinergic Agonists
Anti-Inflammatory Agents
Entire Nervous System
Brain
11
1
12
453
5
Paper Details
References
  • References84
  • Citations538
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  • References84
  • Citations538
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Physiology and immunology of the cholinergic antiinflammatory pathway

The Journal of Clinical Investigation

Feb 3, 2007

Kevin J Tracey

PMID: 17273548

DOI: 10.1172/jci30555

Abstract

Cytokine production by the immune system contributes importantly to both health and disease. The nervous system, via an inflammatory reflex of the vagus nerve, can inhibit cytokine release and thereby prevent tissue injury and death. The efferent neural signaling pathway is termed the c...read more

Mentioned in this Paper

Septicemia
Cholinergic Fibers
Ischemia
Biochemical Pathway
Immune System
Endotoxemia
Cholinergic Agonists
Anti-Inflammatory Agents
Entire Nervous System
Brain
11
1
12
453
5

Similar Papers Found In These Feeds

Paper Details
References
  • References84
  • Citations538
12345...
  • References84
  • Citations538
12345...
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