PMID: 589507Nov 1, 1977

Physostigmine reversal of postoperative somnolence

Canadian Anaesthetists' Society Journal
G E HillC R Sentker


The effects of physostigmine on reversal of post-operative somnolence following general anaesthesia were evaluated in 187 patients. Significant reversal of anaesthetic-induced post-operative somnolence was observed in those patients receiving physostigmine when compared to a control group. These results suggest that general anaesthesia with halothane may be included in those situations where central nervous system depression may be reversed by administration of physostigmine. Cholinergic side-effects observed with physostigmine administration were minimal.


Nov 1, 1976·Canadian Anaesthetists' Society Journal·J Brebner, L Hadley
Jan 1, 1970·Annual Review of Physiology·C Hebb
Feb 1, 1973·The American Journal of Psychiatry·M K el-YousefH J Sekerke
Feb 1, 1971·The American Journal of Psychiatry·J F Heiser, J C Gillin
Sep 1, 1971·Clinical Toxicology·T L SlovisW Lipscomb
Mar 1, 1952·Journal of Neurophysiology·M G LARRABEE, J M POSTERNAK


Jan 1, 1990·Psychopharmacology·M MimuraH Miyake
Jul 1, 1979·Canadian Anaesthetists' Society Journal·J C DrummondP S Young
Jul 1, 1983·Canadian Anaesthetists' Society Journal·A H Maister
Aug 12, 1999·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·C R Ries
May 1, 1985·Canadian Anaesthetists' Society Journal·R S HannallahB S Epstein
Oct 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·D J DehringW T Peruzzi
Feb 3, 1998·Anesthesiology·E P HornJ Schulte am Esch
Jan 1, 1997·European Journal of Anaesthesiology·B Cook, A A Spence
Feb 18, 1998·European Journal of Anaesthesiology·J Link
Nov 1, 1989·Acta Anaesthesiologica Scandinavica·P HartvigL Wiklund
Jan 1, 1988·Acta Anaesthesiologica Scandinavica. Supplementum·E GellerV Rudick
Feb 1, 1982·Acta Anaesthesiologica Scandinavica·E Nilsson, J J Himberg
Oct 1, 1981·Acta Anaesthesiologica Scandinavica·M Salmenperä, E Nilsson
May 1, 1986·Acta Anaesthesiologica Scandinavica·J PeterssonL Wiklund
May 24, 2016·Anesthesia, Essays and Researches·Ullhas Sudhakarrao MisalMudassir Mohd Shaikh
Jun 30, 2017·Journal of Neurophysiology·Robert FongZheng Xie
Sep 22, 2011·Anesthesiology·Ken SoltEmery N Brown
Jan 26, 2007·Acta Anaesthesiologica Scandinavica·K D RöhmS N Piper
Jan 1, 2014·Journal of Neurophysiology·Qiang WangZheng Xie
Feb 28, 2002·Anesthesia and Analgesia·Adia ParaskevaGeorgios Papadopoulos

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